Structure-based discovery of human l-xylulose reductase inhibitors from database screening and molecular docking Fulltext Access 12 Pages 2005
Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-I Fulltext Access 12 Pages 2005
Cardiac Resynchronization Therapy (CRT) in Heart Failure-A Model to Assess the Economic Value of this New Medical Technology Fulltext Access 12 Pages 2005
Cost-Effectiveness of Recombinant Human Erythropoietin for Reducing Red Blood Cells Transfusions in Critically Ill Patients Fulltext Access 12 Pages 2005
Patterns and Effectiveness of Lipid-Lowering Therapies in a Managed Care Environment Fulltext Access 12 Pages 2005
Significance of synthetic nanostructures in dictating cellular response Fulltext Access 12 Pages 2005
Modeling and characterization of a nanoliter drug-delivery MEMS micropump with circular bossed membrane Fulltext Access 12 Pages 2005
Evaluating user interactions with clinical information systems: A model based on human-computer interaction models Fulltext Access 12 Pages 2005
The use of receiver operating characteristic curves in biomedical informatics Fulltext Access 12 Pages 2005
Synthesis and anti-viral activity of a series of d- and l-2â²-deoxy-2â²-fluororibonucleosides in the subgenomic HCV replicon system Fulltext Access 12 Pages 2005
A new method for sleep apnea classification using wavelets and feedforward neural networks Fulltext Access 12 Pages 2005
Identification of signatures in biomedical spectra using domain knowledge Fulltext Access 12 Pages 2005
Modelling and multivariable control in anaesthesia using neural-fuzzy paradigms Fulltext Access 12 Pages 2005
Advanced MR Imaging of Acute Stroke: The University of California at Los Angeles Endovascular Therapy Experience Fulltext Access 12 Pages 2005
Place de l'imagerie de perfusion par irm dans la prise en charge des tumeurs cérébrales, gliales en particulier Fulltext Access 12 Pages 2005
Characterizing Speech and Language Pathology Outcomes in Stroke Rehabilitation Fulltext Access 12 Pages 2005
ESR spin trapping of a carbon-centered free radical from agonist-stimulated human platelets Fulltext Access 12 Pages 2005
Histochemical localization of complex carbohydrates in the nasolabial glands of the Japanese deer (Cervus nippon yakushimae) Fulltext Access 12 Pages 2005
Possible autocrine regulation of chromaffin cell activity in adrenal glands of the frog by endothelin-1-induced serotonin release Fulltext Access 12 Pages 2005
SYBR Green I-induced fluorescence in cultured immune cells: A comparison with Acridine Orange Fulltext Access 12 Pages 2005
Hypoxia-reoxygenation-induced mitochondrial damage and apoptosis in human endothelial cells are inhibited by vitamin C Fulltext Access 12 Pages 2005
Protein phosphatase 1α is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr Fulltext Access 12 Pages 2005
Crystal and microparticle effects on MDCK cell superoxide production: oxalate-specific mitochondrial membrane potential changes Fulltext Access 12 Pages 2005
Cytotoxicity studies of chromium(III) complexes on human dermal fibroblasts Fulltext Access 12 Pages 2005
Tempol diverts peroxynitrite/carbon dioxide reactivity toward albumin and cells from protein-tyrosine nitration to protein-cysteine nitrosation Fulltext Access 12 Pages 2005
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite Fulltext Access 12 Pages 2005
Planning and execution processes in speech control by fluent speakers and speakers who stutter Fulltext Access 12 Pages 2005
Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy Fulltext Access 12 Pages 2005
Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells Fulltext Access 12 Pages 2005
Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition Fulltext Access 12 Pages 2005
Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic Fulltext Access 12 Pages 2005
Evaluation of a new copper(II)-curcumin complex as superoxide dismutase mimic and its free radical reactions Fulltext Access 12 Pages 2005
Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line Fulltext Access 12 Pages 2005
Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives Fulltext Access 12 Pages 2005
Natural and synthetic cage compounds incorporating the 2,9,10-trioxatricyclo[4.3.1.03,8]decane type moiety Fulltext Access 12 Pages 2005
Non-stochastic and stochastic linear indices of the 'molecular pseudograph's atom adjacency matrix': application to 'in silico' studies for the rational discovery of new antimalarial compounds Fulltext Access 12 Pages 2005
Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3â²-C-ethynyluridine (EUrd) and 3â²-C-ethynylcytidine (ECyd) Fulltext Access 12 Pages 2005
Modified mannose disaccharides as substrates and inhibitors of a polyprenol monophosphomannose-dependent α-(1â6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis Fulltext Access 12 Pages 2005
Structure–activity studies of 3′-4′-dichloro-meperidine analogues at dopamine and serotonin transporters Fulltext Access 12 Pages 2005
Design, synthesis and evaluation of carbazole derivatives as PPARα/γ dual agonists and antioxidants Fulltext Access 12 Pages 2005
Synthesis of 2-(aminocarbonylmethylthio)-1H-imidazoles as novel Capravirine analogues Fulltext Access 12 Pages 2005
Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities Fulltext Access 12 Pages 2005
A topological substructural approach applied to the computational prediction of rodent carcinogenicity Fulltext Access 12 Pages 2005
Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors Fulltext Access 12 Pages 2005
Aminoethyl-substituted indole-3-acetic acids for the preparation of tagged and carrier-linked auxin Fulltext Access 12 Pages 2005
Eugenol and its structural analogs inhibit monoamine oxidase A and exhibit antidepressant-like activity Fulltext Access 12 Pages 2005
Relationships between structure and high-throughput screening permeability of diverse drugs with artificial membranes: Application to prediction of Caco-2 cell permeability Fulltext Access 12 Pages 2005
Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists Fulltext Access 12 Pages 2005
Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation Fulltext Access 12 Pages 2005
Preventive effects of soyasapogenol B derivatives on liver injury in a concanavalin A-induced hepatitis model Fulltext Access 12 Pages 2005
Synthesis and antitubercular activities of bis-glycosylated diamino alcohols Fulltext Access 12 Pages 2005
Differences between the structural requirements for ABA 8′-hydroxylase inhibition and for ABA activity Fulltext Access 12 Pages 2005
Highly antiproliferative, low-calcemic, side-chain ketone analogs of the hormone 1α,25-dihydroxyvitamin D3 Fulltext Access 12 Pages 2005
New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation Fulltext Access 12 Pages 2005
Stereocontrolled synthesis of anticancer β-lactams via the Staudinger reaction Fulltext Access 12 Pages 2005
A novel non-stochastic quadratic fingerprints-based approach for the ‘in silico’ discovery of new antitrypanosomal compounds Fulltext Access 12 Pages 2005
Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes Fulltext Access 12 Pages 2005
Synthesis and evaluation of molluscicidal and larvicidal activities of some novel enaminones derived from 4-hydroxyquinolinones: Part IX Fulltext Access 12 Pages 2005
Ginkgolides and bilobalide: Their physical, chromatographic and spectroscopic properties Fulltext Access 12 Pages 2005
Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds Fulltext Access 12 Pages 2005
Methyltrioxorhenium catalysed synthesis of highly oxidised aryltetralin lignans with anti-topoisomerase II and apoptogenic activities Fulltext Access 12 Pages 2005
Triketones active against antibiotic-resistant bacteria: Synthesis, structure–activity relationships, and mode of action Fulltext Access 12 Pages 2005
The general public's information needs and perceptions regarding hereditary cancer: an application of the Integrated Change Model Fulltext Access 12 Pages 2005
A comparative investigation of the speech-associated attitude of preschool and kindergarten children who do and do not stutter Fulltext Access 12 Pages 2005
A model of motor control of the nematode C. elegans with neuronal circuits Fulltext Access 12 Pages 2005
SiMCAL 1 algorithm for analysis of gene expression data related to the phosphatidylserine receptor Fulltext Access 12 Pages 2005
La ecografÃa musculoesquelética como prueba diagnóstica en el hombro doloroso (I) Fulltext Access 12 Pages 2005
Perinatal care regionalization and acceptability by professionals in France Fulltext Access 12 Pages 2005
Dementia Care: Critical Interactions Among Primary Care Physicians, Patients and Caregivers Fulltext Access 12 Pages 2005
Traitement chirurgical de la maladie thromboembolique pulmonaire chronique Fulltext Access 12 Pages 2005
PDT with TOOKAD® studied in the chorioallantoic membrane of fertilized eggs Fulltext Access 12 Pages 2005
Exploration of orally available calpain inhibitors: Peptidyl α-ketoamides containing an amphiphile at P3 site Fulltext Access 12 Pages 2005
Information needs and sources of information among cancer patients: a systematic review of research (1980-2003) Fulltext Access 12 Pages 2005
Social support in diabetes: a systematic review of controlled intervention studies Fulltext Access 12 Pages 2005
General synthesis and biological evaluation of α-1-C-substituted derivatives of fagomine (2-deoxynojirimycin-α-C-glycosides) Fulltext Access 12 Pages 2005
A novel method of estimation of lipophilicity using distance-based topological indices: dominating role of equalized electronegativity Fulltext Access 12 Pages 2005
In silico ADME modelling: prediction models for blood–brain barrier permeation using a systematic variable selection method Fulltext Access 12 Pages 2005
Synthesis and biological evaluation of penam sulfones as inhibitors of β-lactamases Fulltext Access 12 Pages 2005
Synthesis and antibody-binding studies of a series of parasite fuco-oligosaccharides Fulltext Access 12 Pages 2005