Quantifying Dry Milling in Pharmaceutical Processing: A Review on Experimental and Modeling Approaches Fulltext Access 13 Pages 2015
Modulation of signal transduction pathways by natural compounds in cancer Fulltext Access 13 Pages 2015
Bradykinin in ischemic conditioning-induced tissue protection: Evidences and possible mechanisms Fulltext Access 13 Pages 2015
Corticotropin-releasing factor 1 receptor mediates the activity of the reward system evoked by morphine-induced conditioned place preference Fulltext Access 13 Pages 2015
An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity Fulltext Access 13 Pages 2015
The impact of patients' perceptions of the listening skills of the pharmacist on their willingness to re-use Home Medicines Reviews: A structural equation model Fulltext Access 13 Pages 2015
Do depressed patients on adjunctive atypical antipsychotics demonstrate a better quality of life compared to those on antidepressants only? A comparative cross-sectional study of a nationally representative sample of the US population Fulltext Access 13 Pages 2015
Impact of Prolonged-release Oxycodone/Naloxone on Outcomes Affecting Patients' Daily Functioning in Comparison With Extended-release Tapentadol: A Systematic Review Fulltext Access 13 Pages 2015
Neurobiological studies of chronic pain and analgesia: Rationale and refinements Fulltext Access 13 Pages 2015
The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited Fulltext Access 13 Pages 2015
Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity Fulltext Access 13 Pages 2015
Simulation of Metabolic Drug-Drug Interactions Perpetrated by Fluvoxamine Using Hybridized Two-Compartment Hepatic Drug-Pool-Based Tube Modeling and Estimation of In Vivo Inhibition Constants Fulltext Access 13 Pages 2015
Pozytywna i negatywna adaptacja dzieci i młodzieży rodziców uzależnionych od alkoholu Fulltext Access 13 Pages 2015
Physicochemical Characterization of Cyclodextrin-Drug Interactions in the Solid State and the Effect of Water on These Interactions Fulltext Access 13 Pages 2015
Systematic Screening of Different Surface Modifiers for the Production of Physically Stable Nanosuspensions Fulltext Access 13 Pages 2015
A Pharmacokinetic Model for Quantifying the Effect of Vascular Permeability on the Choice of Drug Carrier: A Framework for Personalized Nanomedicine Fulltext Access 13 Pages 2015
Coupling in the cortico-basal ganglia circuit is aberrant in the ketamine model of schizophrenia Fulltext Access 13 Pages 2015
The cannabinoid system and visual processing: A review on experimental findings and clinical presumptions Fulltext Access 13 Pages 2015
Cognitive heterogeneity in adult attention deficit/hyperactivity disorder: A systematic analysis of neuropsychological measurements Fulltext Access 13 Pages 2015
Contribution of genes and unique environment to cross-sectional and longitudinal measures of subcortical volumes in bipolar disorder Fulltext Access 13 Pages 2015
Repeated amphetamine administration and long-term effects on 50-kHz ultrasonic vocalizations: Possible relevance to the motivational and dopamine-stimulating properties of the drug Fulltext Access 13 Pages 2015
Antiadenovirus drug discovery: potential targets and evaluation methodologies Fulltext Access 13 Pages 2015
The opportunities of mining historical and collective data in drug discovery Fulltext Access 13 Pages 2015
A low-cost, high-quality new drug discovery process using patient-derived induced pluripotent stem cells Fulltext Access 13 Pages 2015
Application of Physiologically Based Absorption Modeling for Amphetamine Salts Drug Products in Generic Drug Evaluation Fulltext Access 13 Pages 2015
Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease Fulltext Access 13 Pages 2015
Nanostructured lipid carrier system for topical delivery of terbinafine hydrochloride Fulltext Access 13 Pages 2015
Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability Fulltext Access 13 Pages 2015
Herbal drugs against cardiovascular disease: traditional medicine and modern development Fulltext Access 13 Pages 2015
Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies Fulltext Access 13 Pages 2015
Type 4 phosphodiesterase enzyme inhibitor, rolipram rescues behavioral deficits in olfactory bulbectomy models of depression: Involvement of hypothalamic–pituitary–adrenal axis, cAMP signaling aspects and antioxidant defense system Fulltext Access 13 Pages 2015
A Novel Combined Micellar System of Lapatinib and Paclitaxel with Enhanced Antineoplastic Effect Against Human Epidermal Growth Factor Receptor-2 Positive Breast Tumor In Vitro Fulltext Access 13 Pages 2015
Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis Fulltext Access 13 Pages 2015
The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation Fulltext Access 13 Pages 2015
Zasoby odpornościowe i czynniki ryzyka a używanie alkoholu i marihuany w okresie wczesnej dorosłości Fulltext Access 13 Pages 2015
Treatment patterns among breast cancer patients in the United States using two national surveys on visits to physicians' offices and hospital outpatient departments Fulltext Access 13 Pages 2015
Characterization of the lipopolysaccharide induced model of Parkinson's disease: Role of oxidative stress and neuroinflammation Fulltext Access 14 Pages 2015
Drug-Drug Interactions Related to Altered Absorption and Plasma Protein Binding: Theoretical and Regulatory Considerations, and an Industry Perspective Fulltext Access 14 Pages 2015
Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors Fulltext Access 14 Pages 2015
Challenges and achievements in the therapeutic modulation of aquaporin functionality Fulltext Access 14 Pages 2015
Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 2: Topical Drug Product Fulltext Access 14 Pages 2015
Fitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can Fly Fulltext Access 14 Pages 2015
Assessment of serum biomarkers in rats after exposure to pesticides of different chemical classes Fulltext Access 14 Pages 2015
Virus-induced modulation of lower airway diseases: Pathogenesis and pharmacologic approaches to treatment Fulltext Access 14 Pages 2015
Quality by Design Coupled with Near Infrared in Formulation of Transdermal Glimepiride Liposomal Films Fulltext Access 14 Pages 2015
The mechanisms of action of flavonoids in the brain: Direct versus indirect effects Fulltext Access 14 Pages 2015
Polymorphism in Sulfadimidine/4-Aminosalicylic Acid Cocrystals: Solid-State Characterization and Physicochemical Properties Fulltext Access 14 Pages 2015
Use of Three-Compartment Physiologically Based Pharmacokinetic Modeling to Predict Hepatic Blood Levels of Fluvoxamine Relevant for Drug-Drug Interactions Fulltext Access 14 Pages 2015
Free Fatty Acid Particles in Protein Formulations, Part 1: Microspectroscopic Identification Fulltext Access 14 Pages 2015
Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress Fulltext Access 14 Pages 2015
Hypertension exacerbates predisposition to neurodegeneration and memory impairment in the presence of a neuroinflammatory stimulus: Protection by angiotensin converting enzyme inhibition Fulltext Access 14 Pages 2015
Clinical implications of leukocyte infiltration at the choroid plexus in (neuro)inflammatory disorders Fulltext Access 14 Pages 2015
Molecular perspectives on solid-state phase transformation and chemical reactivity of drugs: metoclopramide as an example Fulltext Access 14 Pages 2015
Machine-learning approaches in drug discovery: methods and applications Fulltext Access 14 Pages 2015
The potential of inhibitors of endocannabinoid metabolism as anxiolytic and antidepressive drugs—A practical view Fulltext Access 14 Pages 2015
Community, autonomy and bespoke services: Independent community pharmacy practice in hyperdiverse, London communities Fulltext Access 14 Pages 2015
Internationally trained pharmacists' perception of their communication proficiency and their views on the impact on patient safety Fulltext Access 14 Pages 2015
Past, present and perspectives of Manipur traditional medicine: A major health care system available for rural population in the North-East India Fulltext Access 14 Pages 2015
Epithelial–mesenchymal transition in human cancer: Comprehensive reprogramming of metabolism, epigenetics, and differentiation Fulltext Access 14 Pages 2015
Application of physiologically-based pharmacokinetic modeling to explore the role of kidney transporters in renal reabsorption of perfluorooctanoic acid in the rat Fulltext Access 14 Pages 2015
Curcumin enhances recovery of pancreatic islets from cellular stress induced inflammation and apoptosis in diabetic rats Fulltext Access 14 Pages 2015
Oral repeated-dose systemic and reproductive toxicity of 6:2 fluorotelomer alcohol in mice Fulltext Access 14 Pages 2015
Comparative metal oxide nanoparticle toxicity using embryonic zebrafish Fulltext Access 14 Pages 2015
Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling Fulltext Access 14 Pages 2015
Contribution of oxidative stress and prostanoids in endothelial dysfunction induced by chronic fluoxetine treatment Fulltext Access 14 Pages 2015
Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons Fulltext Access 14 Pages 2015
Amphetamine sensitization in mice is sufficient to produce both manic- and depressive-related behaviors as well as changes in the functional connectivity of corticolimbic structures Fulltext Access 14 Pages 2015
Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: A comparison with carbamazepine, oxcarbazepine and lacosamide Fulltext Access 14 Pages 2015
Perspective of community pharmacists on their practice with patients who have an antidepressant drug treatment: Findings from a focus group study Fulltext Access 14 Pages 2015
Original ResearchPopulation Pharmacokinetic and Pharmacodynamic Modeling and Effects on Platelet Counts of Different Dosages of Eltrombopag in Chinese Patients With Chronic Primary Immune Thrombocytopenia Fulltext Access 14 Pages 2015
Review ArticleRole of the Pharmacist in Medication Therapy Management Services in Patients With Osteoporosis Fulltext Access 14 Pages 2015
An Assessment of the Pharmacokinetics of a Sustained-release Formulation of a Tramadol/Acetaminophen Combination in Healthy Subjects Fulltext Access 14 Pages 2015
Pharmacokinetic Properties and Tolerability of Low-dose SoluMatrix Diclofenac Fulltext Access 14 Pages 2015
Extemporaneous Formulations of Metformin for Pediatric Endocrinology: Physicochemical Integrity, Cytotoxicity of Sweeteners, and Quantitation of Plasma Levels Fulltext Access 14 Pages 2015
Limited Impact of Drug Exposure Misclassification From Non-Benefit Thiazolidinedione Drug Use on Mortality and Hospitalizations From Saskatchewan, Canada: A Cohort Study Fulltext Access 14 Pages 2015
Gut Microbiota: The Conductor in the Orchestra of Immune-Neuroendocrine Communication Fulltext Access 14 Pages 2015
Economic Comparison of an Empirical Versus Diagnostic-Driven Strategy for Treating Invasive Fungal Disease in Immunocompromised Patients Fulltext Access 14 Pages 2015
Barriers and facilitators of medication reconciliation processes for recently discharged patients from community pharmacists' perspectives Fulltext Access 14 Pages 2015
Developability Assessment During the Selection of Novel Therapeutic Antibodies Fulltext Access 14 Pages 2015
Development and Characterization of a Hydrogel Containing Silver Sulfadiazine for Antimicrobial Topical Applications Fulltext Access 14 Pages 2015