Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential Fulltext Access 14 Pages 2007
Comparison of the QT interval response during sinus and paced rhythm in conscious and anesthetized beagle dogs Fulltext Access 14 Pages 2007
Isolated heart perfusion according to Langendorff—Still viable in the new millennium Fulltext Access 14 Pages 2007
Ethnopharmacological survey of the Bunda district, Tanzania: Plants used to treat infectious diseases Fulltext Access 14 Pages 2007
Proteome of human T lymphocytes with treatment of cyclosporine and polysaccharopeptide: Analysis of significant proteins that manipulate T cells proliferation and immunosuppression Fulltext Access 14 Pages 2007
d-pinitol inhibits Th1 polarization via the suppression of dendritic cells Fulltext Access 14 Pages 2007
Shrimp (Penaeus monodon) anti-lipopolysaccharide factor reduces the lethality of Pseudomonas aeruginosa sepsis in mice Fulltext Access 14 Pages 2007
Molecular genetics and mechanisms of apoptosis in carcinomas of the lung and pleura: Therapeutic targets Fulltext Access 14 Pages 2007
Behavioral and neuropharmacological characterization of nicotine as a conditional stimulus Fulltext Access 14 Pages 2007
Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species Fulltext Access 14 Pages 2007
Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat Fulltext Access 14 Pages 2007
A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog Fulltext Access 14 Pages 2007
Altered gene expression in human leukemia K562 cells selected for resistance to etoposide Fulltext Access 14 Pages 2007
Activation of thromboxane receptor α induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells Fulltext Access 14 Pages 2007
Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors Fulltext Access 14 Pages 2007
DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)] Fulltext Access 14 Pages 2007
Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24) Fulltext Access 14 Pages 2007
Use of comprehensive screening methods to detect selective human CAR activators Fulltext Access 14 Pages 2007
A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides Fulltext Access 14 Pages 2007
Induction of c-Fos and zif268 in the nociceptive amygdala parallel abstinence hyperalgesia in rats briefly exposed to morphine Fulltext Access 14 Pages 2007
Antinociception mediated by α2-adrenergic activation involves increasing tumor necrosis factor α (TNFα) expression and restoring TNFα and α2-adrenergic inhibition of norepinephrine release Fulltext Access 14 Pages 2007
Nerve growth factor sequestering therapy attenuates non-malignant skeletal pain following fracture Fulltext Access 14 Pages 2007
Differential protein expression of peroxiredoxin I and II by benzo(a)pyrene and quercetin treatment in 22Rv1 and PrEC prostate cell lines Fulltext Access 14 Pages 2007
Activation of protein kinase C and disruption of endothelial monolayer integrity by sodium arsenite—Potential mechanism in the development of atherosclerosis Fulltext Access 14 Pages 2007
Comparative molecular pathology of cadmium- and all-trans-retinoic acid-induced postaxial forelimb ectrodactyly Fulltext Access 14 Pages 2007
Quantitative structure carcinogenicity relationship for detecting structural alerts in nitroso-compounds Fulltext Access 14 Pages 2007
Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: Effects on apoptosis, necrosis, and glutathione status Fulltext Access 14 Pages 2007
Soluble metals in residual oil fly ash alter innate and adaptive pulmonary immune responses to bacterial infection in rats Fulltext Access 14 Pages 2007
Sexually dimorphic gene regulation in brain as a target for endocrine disrupters: Developmental exposure of rats to 4-methylbenzylidene camphor Fulltext Access 14 Pages 2007
Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: Discordant in vitro and in vivo dose-effects: A review Fulltext Access 14 Pages 2007
Advances in asthma and COPD management: Delivering CFC-free inhaled therapy using Modulite® technology Fulltext Access 14 Pages 2007
Noradrenergic facilitation of shock-probe defensive burying in lateral septum of rats, and modulation by chronic treatment with desipramine Fulltext Access 14 Pages 2007
Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors Fulltext Access 14 Pages 2007
Transglutaminase 2 inhibitors and their therapeutic role in disease states Fulltext Access 14 Pages 2007
The pharmacology of particulate matter air pollution-induced cardiovascular dysfunction Fulltext Access 14 Pages 2007
A novel therapeutic target in various lung diseases: Airway proteases and protease-activated receptors Fulltext Access 14 Pages 2007
Potassium channel diversity in the pulmonary arteries and pulmonary veins: Implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension Fulltext Access 14 Pages 2007
Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury Fulltext Access 14 Pages 2007
A standardized root extract of Withania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice Fulltext Access 14 Pages 2007
Detection of hypoxia-related proteins in medaka (Oryzias latipes) brain tissue by difference gel electrophoresis and de novo sequencing of 4-sulfophenyl isothiocyanate-derivatized peptides by matrix-assisted laser desorption/ionization time-of-flight mass Fulltext Access 14 Pages 2007
The expression of TRH, its receptors and degrading enzyme is differentially modulated in the rat limbic system during training in the Morris water maze Fulltext Access 14 Pages 2007
Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: Relevance to oxidative damage in Parkinson's disease Fulltext Access 14 Pages 2007
Neuronal regulation by which microglia enhance the production of neurotrophic factors for GABAergic, catecholaminergic, and cholinergic neurons Fulltext Access 14 Pages 2007
Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage Fulltext Access 14 Pages 2007
Existence of high and low affinity dinucleotides pentaphosphate-induced calcium responses in individual synaptic terminals and lack of correlation with the distribution of P2X1–7 subunits Fulltext Access 14 Pages 2007
Some rewarding effects of androgens may be mediated by actions of its 5α-reduced metabolite 3α-androstanediol Fulltext Access 14 Pages 2007
HPA function in adolescence: Role of sex hormones in its regulation and the enduring consequences of exposure to stressors Fulltext Access 14 Pages 2007
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein Fulltext Access 14 Pages 2007
Selected oxidative stress markers in a South American crocodilian species Fulltext Access 14 Pages 2007
Pollution biomarkers in estuarine animals: Critical review and new perspectives Fulltext Access 14 Pages 2007
Reactive cysteine in proteins: Protein folding, antioxidant defense, redox signaling and more Fulltext Access 14 Pages 2007
Biochemistry of insect epicuticle degradation by entomopathogenic fungi Fulltext Access 14 Pages 2007
A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain Fulltext Access 14 Pages 2007
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice Fulltext Access 14 Pages 2007
Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain-related sensitization of amygdala neurons Fulltext Access 14 Pages 2007
Long-lasting behavioral effects of juvenile trauma in an animal model of PTSD associated with a failure of the autonomic nervous system to recover Fulltext Access 14 Pages 2007
Effects of salts on protein-surface interactions: applications for column chromatography Fulltext Access 14 Pages 2007
High Concentration Formulation Feasibility of Human Immunoglubulin G for Subcutaneous Administration Fulltext Access 14 Pages 2007
Effects of Solutes on Empirical Phase Diagrams of Human Fibroblast Growth Factor 1 Fulltext Access 14 Pages 2007
Circulatory Transport and Capillary-Tissue Exchange as Determinants of the Distribution Kinetics of Inulin and Antipyrine in Dog Fulltext Access 14 Pages 2007
Chemoinformetrical Evaluation of Dissolution Property of Indomethacin Tablets by Near-Infrared Spectroscopy Fulltext Access 14 Pages 2007
Development and characterization of chitosan succinate microspheres for the improved oral bioavailability of insulin Fulltext Access 14 Pages 2007
Novel screening assay for antioxidant protection against peroxyl radicalâinduced loss of protein function Fulltext Access 14 Pages 2007
The Pharmacodynamic Effects of Sirolimus andSirolimus-Calcineurin Inhibitor Combinations on Macrophage Scavenger and Nuclear Hormone Receptors Fulltext Access 14 Pages 2007
Probing Pseudopolymorphic Transitions in Pharmaceutical Solids using Raman Spectroscopy: Hydration and Dehydration of Theophylline Fulltext Access 14 Pages 2007
Mechanistic Study of the Effect of Roller Compaction and Lubricant on Tablet Mechanical Strength Fulltext Access 14 Pages 2007
The Effect of Annealing on the Stability of Amorphous Solids: Chemical Stability of Freeze-Dried Moxalactam Fulltext Access 14 Pages 2007
Demonstration of a Shear-Based Solid-State Phase Transformation in a Small Molecular organic System: Chlorpropamide Fulltext Access 14 Pages 2007
Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia–ischemia in adult rats Fulltext Access 14 Pages 2007
Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice Fulltext Access 14 Pages 2007
Antibacterial Activity of Contact Lenses Bearing Surface-Immobilized Layers of Intact Liposomes Loaded With Levofloxacin Fulltext Access 14 Pages 2007
Dextran or Hydroxyethyl Starch in Sprayfreeze-Dried Trehalose/Mannitol Microparticles Intended as Ballistic Particulate Carriers for Proteins Fulltext Access 14 Pages 2007
Differential effects of adjunctive methylphenidate and citalopram on extracellular levels of serotonin, noradrenaline and dopamine in the rat brain Fulltext Access 14 Pages 2007
Impact of Cremophor-EL and Polysorbate-80 on Digoxin Permeability across Rat Jejunum: Delineation of Thermodynamic and Transporter Related Events Using the Reciprocal Permeability Approach Fulltext Access 14 Pages 2007
Lipid Formulation Strategies for Enhancing Intestinal Transport and Absorption of P-Glycoprotein (P-gp) Substrate Drugs: In vitro/In vivo Case Studies Fulltext Access 14 Pages 2007
The effect of doxapram on brain imaging in patients with panic disorder Fulltext Access 15 Pages 2007
Antipsychotic augmentation of serotonergic antidepressants in treatment-resistant obsessive–compulsive disorder: A meta-analysis of the randomized controlled trials Fulltext Access 15 Pages 2007
Molecular characterization and tissue distribution of aryl hydrocarbon receptor nuclear translocator isoforms, ARNT1 and ARNT2, and identification of novel splice variants in common cormorant (Phalacrocorax carbo) Fulltext Access 15 Pages 2007
A New Paradigm for Numerical Simulation of Microneedle-Based Drug Delivery Aided by Histology of Microneedle-Pierced Skin Fulltext Access 15 Pages 2007
Population Pharmacokinetics, Brain Distribution, and Pharmacodynamics of 2nd Generation Dopamine Transporter Selective Benztropine Analogs Developed as Potential Substitute Therapeutics for Treatment of Cocaine Abuse Fulltext Access 15 Pages 2007