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Daneshyari Pharmacology, Toxicology and Pharmaceutics (General) Journas Latest Articles

Pharmacology, Toxicology and Pharmaceutics (General) Research Articles

Expanding the scope of chemoselective peptide ligations in chemical biology
Fulltext Access 7 Pages 2008
Nanowire sensors for multiplexed detection of biomolecules
Fulltext Access 7 Pages 2008
Fluorescent probes for bioimaging applications
Fulltext Access 7 Pages 2008
Integrating the discovery pipeline for novel compounds targeting ion channels
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Mitochondrial drugs
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Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations
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Olefin metathesis for chemical biology
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Biomass to fuels via microbial transformations
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Metal complexes as artificial proteases: toward catalytic drugs
Fulltext Access 7 Pages 2008
Advances in and applications of proteasome inhibitors
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Metals in Alzheimer's and Parkinson's Diseases
Fulltext Access 7 Pages 2008
Fiat Lux: selective delivery of high flux of nitric oxide (NO) to biological targets using photoactive metal nitrosyls
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RNA in motion
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A repulsive field: advances in the electrostatics of the ion atmosphere
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Folding and unfolding single RNA molecules under tension
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RNA folding and ribosome assembly
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Peptides as protein binding site mimetics
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New directions in library design and analysis
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Glycan arrays: biological and medical applications
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Avian influenza virus, a very sticky situation
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Protein misfolding and disease: from the test tube to the organism
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Discovering mechanisms of signaling-mediated cysteine oxidation
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The Sirtuin family: therapeutic targets to treat diseases of aging
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Understanding and exploiting substrate recognition by protein kinases
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Structure-directed combinatorial library design
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Transient oxidation as a mechanistic strategy in enzymatic catalysis
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Coverage and bias in chemical library design
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Computational analysis of ligand relationships within target families
Fulltext Access 7 Pages 2008
Novel leads from Heliotropium ovalifolium, 4,7,8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5,7-dimethoxy-naphthalene-2-carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes
Fulltext Access 8 Pages 2008
The gastric ulcer protective and healing role of cysteine proteinases from Carica candamarcensis
Fulltext Access 8 Pages 2008
Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold
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Cancer chemopreventive activity of “rosin” constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test
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Evaluation of the effects of the herbal product Catuama® in inflammatory and neuropathic models of nociception in rats
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Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system
Fulltext Access 8 Pages 2008
Hypocholesterolemic effect of stilbenes containing extract-fraction from Cajanus cajan L. on diet-induced hypercholesterolemia in mice
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Stimulatory effect of Crocus sativus (saffron) on β2-adrenoceptors of guinea pig tracheal chains
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Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation
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Inhibitory effect of essential oils against herpes simplex virus type 2
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The effect of trans-ferulic acid and gamma-oryzanol on ethanol-induced liver injury in C57BL mouse
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Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells
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The multicomponent phytopharmaceutical SKI306X inhibits in vitro cartilage degradation and the production of inflammatory mediators
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Tissue distribution and excretion of resveratrol in rat after oral administration of Polygonum cuspidatum extract (PCE)
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Radioprotective effects of propolis and quercetin in γ-irradiated mice evaluated by the alkaline comet assay
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Gastroprokinetic effects of DA-9701, a new prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber
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Proteomic analysis of differential protein expression in rat platelets treated with notoginsengnosides
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Positive antibacterial co-action between hop (Humulus lupulus) constituents and selected antibiotics
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Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells
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Effects of tenuifolin extracted from radix polygalae on learning and memory: A behavioral and biochemical study on aged and amnesic mice
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Effect of Echinacea augustifolia extract on cell viability and differentiation in mammary epithelial cells
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Pharmacokinetics and immunomodulatory effects of phytotherapeutic lozenges (bonbons) with Echinacea purpurea extract
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Comparative study on the aristolochic acid I content of Herba Asari for safe use
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20-Hydroxyecdysone increases fiber size in a muscle-specific fashion in rat
Fulltext Access 8 Pages 2008
Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology
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Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: A randomized, double blind placebo controlled trial
Fulltext Access 8 Pages 2008
In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes
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Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells
Fulltext Access 8 Pages 2008
Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin
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Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine
Fulltext Access 8 Pages 2008
Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism
Fulltext Access 8 Pages 2008
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats
Fulltext Access 8 Pages 2008
Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders
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Taspine isolated from Radix et Rhizoma Leonticis inhibits growth of human umbilical vein endothelial cell (HUVEC) by inducing its apoptosis
Fulltext Access 8 Pages 2008
Comparative study of Rhodiola preparations on behavioral despair of rats
Fulltext Access 8 Pages 2008
Tryptophan synthase, an allosteric molecular factory
Fulltext Access 8 Pages 2008
Electron interaction with S6-C60(CF3)12: Energy pool of fullerene cage
Fulltext Access 8 Pages 2008
Development of negative-ion proton-transfer chemical-ionization mass spectrometry (NI-PT-CIMS) for the measurement of gas-phase organic acids in the atmosphere
Fulltext Access 8 Pages 2008
Ion–ion reactions with fixed-charge modified proteins to produce ions in a single, very high charge state
Fulltext Access 8 Pages 2008
Charge inversion of polypeptide anions using protein and dendrimer cations as charge inversion reagents
Fulltext Access 8 Pages 2008
Gas-phase proton affinities of guanidines with heteroalkyl side chains
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Intramolecular methyl migration in the protonated N,N′-dimethylpropane-1,3-diamine and N,N′-dimethylethane-1,2-diamine
Fulltext Access 8 Pages 2008
Identification of a matrix effect in the MC-ICP-MS due to sample purification using ion exchange resin: An isotopic case study of molybdenum
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Calibration of a frequency-scan quadrupole ion trap mass spectrometer for microparticle mass analysis
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Parity alternation of linear ground-state hydrogenated cationic carbon clusters HCnSi+ (n = 1–10)
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Analysis and differentiation of mineral dust by single particle laser mass spectrometry
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Selected ion flow tube mass spectrometry of 3-hydroxybutyric acid, acetone and other ketones in the headspace of aqueous solution and urine
Fulltext Access 8 Pages 2008
Development of a reflectron time-of-flight mass spectrometer for non-destructive analysis of isotope ratios in irradiated B4C pellets—Test measurements on an unirradiated control rod pellet
Fulltext Access 8 Pages 2008
The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments
Fulltext Access 8 Pages 2008
Development of a low power, high mass range mass spectrometer for Mars surface analysis
Fulltext Access 8 Pages 2008
Detection and identification of immobilized low-volatility organophosphates by desorption ionization mass spectrometry
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Fragmentation of phosphorylated and singly charged peptide ions via interaction with metastable atoms
Fulltext Access 8 Pages 2008
Mass spectrometric detection of multiple extended series of neutral highly fucosylated N-acetyllactosamine oligosaccharides in human milk
Fulltext Access 8 Pages 2008
Phenotypic analysis of Atlantic cod hemoglobin chains using a combination of top-down and bottom-up mass spectrometric approaches
Fulltext Access 8 Pages 2008
Artificial β-sheets: chemical models of β-sheets
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Structural genomics and drug discovery: all in the family
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Chemical synthesis in nanosized cavities
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Isocyanide-based multicomponent reactions in drug discovery
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The use of Endopep-MS to detect multiple subtypes of botulinum neurotoxins A, B, E, and F
Fulltext Access 8 Pages 2008
Structural insights into sialic acid enzymology
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Nano-Biophotonics: new tools for chemical nano-analytics
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Mass spectrometry for proteomics
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Accessing natural product biosynthetic processes by mass spectrometry
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Proteomics and diagnostics: Let's Get Specific, again
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Peptoid architectures: elaboration, actuation, and application
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Exploring RNA folding one molecule at a time
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Taking femtosecond snapshots of RNA conformational dynamics and complexity
Fulltext Access 8 Pages 2008
Selective recognition of metal ions by metalloregulatory proteins
Fulltext Access 8 Pages 2008
Advances in laboratory evolution of enzymes
Fulltext Access 8 Pages 2008
An embarrassment of riches: the enzymology of RNA modification
Fulltext Access 8 Pages 2008
Cofactor biosynthesis—still yielding fascinating new biological chemistry
Fulltext Access 8 Pages 2008
Inhibition of transcription factors with small organic molecules
Fulltext Access 8 Pages 2008
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