Mechanism of chloroform-induced renal toxicity: Non-involvement of hepatic cytochrome P450-dependent metabolism Fulltext Access 8 Pages 2008
p53 is involved in inducing testicular apoptosis in mice by the altered redox status following tertiary butyl hydroperoxide treatment Fulltext Access 8 Pages 2008
Cytotoxic and genotoxic effects of tambjamine D, an alkaloid isolated from the nudibranch Tambja eliora, on Chinese hamster lung fibroblasts Fulltext Access 8 Pages 2008
Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae Fulltext Access 8 Pages 2008
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters Fulltext Access 8 Pages 2008
Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice Fulltext Access 8 Pages 2008
Synaptogenetic mechanisms controlling postsynaptic differentiation of the neuromuscular junction are nerve-dependent in human and nerve-independent in mouse C2C12 muscle cultures Fulltext Access 8 Pages 2008
Interaction of β-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter Fulltext Access 8 Pages 2008
Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes Fulltext Access 8 Pages 2008
Novel indoloquinoline derivative, IQDMA, suppresses STAT5 phosphorylation and induces apoptosis in HL-60 cells Fulltext Access 8 Pages 2008
Effect of curcumin analog on γ-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro Fulltext Access 8 Pages 2008
Characterization of the glutathione S-transferase-Mu (GSTM) gene sequence and its expression in the hermaphroditic fish, Kryptolebias marmoratus as a function of development, gender type and chemical exposure Fulltext Access 8 Pages 2008
Blood–brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS Fulltext Access 8 Pages 2008
Trans, trans-2,4-decadienal induced cell proliferation via p27 pathway in human bronchial epithelial cells Fulltext Access 8 Pages 2008
Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice Fulltext Access 8 Pages 2008
Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes Fulltext Access 8 Pages 2008
Bio-distribution and metabolic paths of silica coated CdSeS quantum dots Fulltext Access 8 Pages 2008
The rat red blood cell proteome is altered by priming with 2-butoxyethanol Fulltext Access 8 Pages 2008
A zinc-resistant human epithelial cell line is impaired in cadmium and manganese import Fulltext Access 8 Pages 2008
Antioxidant status of erythrocytes and their response to oxidative challenge in humans with argemone oil poisoning Fulltext Access 8 Pages 2008
Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells Fulltext Access 8 Pages 2008
The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities Fulltext Access 8 Pages 2008
Chlordecone altered hepatic disposition of [14C]cholesterol and plasma cholesterol distribution but not SR-BI or ABCG8 proteins in livers of C57BL/6 mice Fulltext Access 8 Pages 2008
Protective effect of unsymmetrical dichalcogenide, a novel antioxidant agent, in vitro and an in vivo model of brain oxidative damage Fulltext Access 8 Pages 2008
Location, location, locationâ¦site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling Fulltext Access 8 Pages 2008
Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies Fulltext Access 8 Pages 2008
An escort for GPCRs: implications for regulation of receptor density at the cell surface Fulltext Access 8 Pages 2008
Preventive effect of (−)epigallocatechin-gallate (EGCG) on lysosomal enzymes in heart and subcellular fractions in isoproterenol-induced myocardial infarcted Wistar rats Fulltext Access 8 Pages 2008
(1′S)-Acetoxychavicol acetate and its enantiomer inhibit tumor cells proliferation via different mechanisms Fulltext Access 8 Pages 2008
Chloro acridone derivatives as cytotoxic agents active on multidrug-resistant cell lines and their duplex DNA complex studies by electrospray ionization mass spectrometry Fulltext Access 8 Pages 2008
Soapwort saponins trigger clathrin-mediated endocytosis of saporin, a type I ribosome-inactivating protein Fulltext Access 8 Pages 2008
La3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells Fulltext Access 8 Pages 2008
Arsenic-induced neurotoxicity in relation to toxicokinetics: Effects on sciatic nerve proteins Fulltext Access 8 Pages 2008
Anti-proliferative and pro-apoptotic effect of CPT13, a novel camptothecin analog, on human colon cancer HCT8 cell line Fulltext Access 8 Pages 2008
Cytotoxicity of goniothalamin enantiomers in renal cancer cells: Involvement of nitric oxide, apoptosis and autophagy Fulltext Access 8 Pages 2008
Effects of mutant human Ki-rasG12C gene dosage on murine lung tumorigenesis and signaling to its downstream effectors Fulltext Access 8 Pages 2008
Protective effects of vitamin E and curcumin on l-thyroxine-induced rat testicular oxidative stress Fulltext Access 8 Pages 2008
Coplanar polychlorinated biphenyl-induced CYP1A1 is regulated through caveolae signaling in vascular endothelial cells Fulltext Access 8 Pages 2008
Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line Fulltext Access 8 Pages 2008
The antidiabetic effects of cysteinyl metformin, a newly synthesized agent, in alloxan- and streptozocin-induced diabetic rats Fulltext Access 8 Pages 2008
Hydroquinone-induced genotoxicity and oxidative DNA damage in HepG2 cells Fulltext Access 8 Pages 2008
The use of PSA as biomarker in nutritional intervention studies of prostate cancer Fulltext Access 8 Pages 2008
Antioxidant-mediated protective effect of potato peel extract in erythrocytes against oxidative damage Fulltext Access 8 Pages 2008
Tetrazolium violet inhibits cell growth and induces cell death in C127 mouse breast tumor cells Fulltext Access 8 Pages 2008
Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model Fulltext Access 8 Pages 2008
Influence of chalcone analogues on serum glucose levels in hyperglycemic rats Fulltext Access 8 Pages 2008
Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice Fulltext Access 8 Pages 2008
In utero exposure to benzene increases embryonic c-Myb and Pim-1 protein levels in CD-1 mice Fulltext Access 8 Pages 2008
Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic Fulltext Access 8 Pages 2008
Interleukin-6 production by peritoneal mesothelial cells and its regulation by inflammatory factors in rats administered carbon tetrachloride intraperitoneally Fulltext Access 8 Pages 2008
Regulation of p53, nuclear factor κB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin Fulltext Access 8 Pages 2008
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis Fulltext Access 8 Pages 2008
Urinary 8-hydroxydeoxyguanosine and urothelial carcinoma risk in low arsenic exposure area Fulltext Access 8 Pages 2008
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and β-adrenergic receptor signaling pathways Fulltext Access 8 Pages 2008
Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro Fulltext Access 8 Pages 2008
Alterations in mitochondrial respiratory functions, redox metabolism and apoptosis by oxidant 4-hydroxynonenal and antioxidants curcumin and melatonin in PC12 cells Fulltext Access 8 Pages 2008
The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone Fulltext Access 8 Pages 2008
Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid Fulltext Access 8 Pages 2008
Suppression of a DNA base excision repair gene, hOGG1, increases bleomycin sensitivity of human lung cancer cell line Fulltext Access 8 Pages 2008
Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity Fulltext Access 8 Pages 2008
LY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanism Fulltext Access 8 Pages 2008
Aromatase inhibition by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts - A comparative study Fulltext Access 8 Pages 2008
In vivo immunomodulatory effects of Antrodia camphorata polysaccharides in a T1/T2 doubly transgenic mouse model for inhibiting infection of Schistosoma mansoni Fulltext Access 8 Pages 2008
Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells Fulltext Access 8 Pages 2008
Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury Fulltext Access 8 Pages 2008
PON1Q192R genetic polymorphism modifies organophosphorous pesticide effects on semen quality and DNA integrity in agricultural workers from southern Mexico Fulltext Access 8 Pages 2008
Activation of oxidative stress-responsive signaling pathways in early splenotoxic response of aniline Fulltext Access 8 Pages 2008
The effects of subchronic acrylamide exposure on gene expression, neurochemistry, hormones, and histopathology in the hypothalamus–pituitary–thyroid axis of male Fischer 344 rats Fulltext Access 8 Pages 2008
Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron Fulltext Access 8 Pages 2008
Internalization of mesoporous silica nanoparticles induces transient but not sufficient osteogenic signals in human mesenchymal stem cells Fulltext Access 8 Pages 2008
A structure–activity analysis of the variation in oxime efficacy against nerve agents Fulltext Access 8 Pages 2008
Involvement of Bcl-xL degradation and mitochondrial-mediated apoptotic pathway in pyrrolizidine alkaloids-induced apoptosis in hepatocytes Fulltext Access 8 Pages 2008
Therapy against organophosphate poisoning: The importance of anticholinergic drugs with antiglutamatergic properties Fulltext Access 8 Pages 2008
Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway Fulltext Access 8 Pages 2008
Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease Fulltext Access 8 Pages 2008
Surface active stabilizer Tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells Fulltext Access 8 Pages 2008
ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta Fulltext Access 8 Pages 2008
Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels Fulltext Access 8 Pages 2008
Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F1 mice Fulltext Access 8 Pages 2008
Role of ARF6 in internalization of metal-binding proteins, metallothionein and transferrin, and cadmium-metallothionein toxicity in kidney proximal tubule cells Fulltext Access 8 Pages 2008
JWA is required for arsenic trioxide induced apoptosis in HeLa and MCF-7 cells via reactive oxygen species and mitochondria linked signal pathway Fulltext Access 8 Pages 2008
The risk of arsenic induced skin lesions in Bangladeshi men and women is affected by arsenic metabolism and the age at first exposure Fulltext Access 8 Pages 2008
Variation in the ovine cortisol response to systemic bacterial endotoxin challenge is predominantly determined by signalling within the hypothalamic–pituitary–adrenal axis Fulltext Access 8 Pages 2008
Immunotoxicity of aflatoxin B1: Impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression Fulltext Access 8 Pages 2008
Ibuprofen administration attenuates serum TNF-α levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation Fulltext Access 8 Pages 2008
Reaction mechanism underlying the in vitro transformation of thioarsenicals Fulltext Access 8 Pages 2008
Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1 Fulltext Access 8 Pages 2008
Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water Fulltext Access 8 Pages 2008
Inhalation of the nerve gas sarin impairs ventilatory responses to hypercapnia and hypoxia in rats Fulltext Access 8 Pages 2008
Cellular function of neuropathy target esterase in lysophosphatidylcholine action Fulltext Access 8 Pages 2008
Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes Fulltext Access 8 Pages 2008
Association of oxidative stress with arsenic methylation in chronic arsenic-exposed children and adults Fulltext Access 8 Pages 2008
Estrogen-induced breast cancer: Alterations in breast morphology and oxidative stress as a function of estrogen exposure Fulltext Access 8 Pages 2008
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile Fulltext Access 8 Pages 2008