Comparative study on the aristolochic acid I content of Herba Asari for safe use Fulltext Access 8 Pages 2008
The multicomponent phytopharmaceutical SKI306X inhibits in vitro cartilage degradation and the production of inflammatory mediators Fulltext Access 8 Pages 2008
Tissue distribution and excretion of resveratrol in rat after oral administration of Polygonum cuspidatum extract (PCE) Fulltext Access 8 Pages 2008
Radioprotective effects of propolis and quercetin in γ-irradiated mice evaluated by the alkaline comet assay Fulltext Access 8 Pages 2008
Gastroprokinetic effects of DA-9701, a new prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber Fulltext Access 8 Pages 2008
Proteomic analysis of differential protein expression in rat platelets treated with notoginsengnosides Fulltext Access 8 Pages 2008
Positive antibacterial co-action between hop (Humulus lupulus) constituents and selected antibiotics Fulltext Access 8 Pages 2008
Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells Fulltext Access 8 Pages 2008
Effects of tenuifolin extracted from radix polygalae on learning and memory: A behavioral and biochemical study on aged and amnesic mice Fulltext Access 8 Pages 2008
Effect of Echinacea augustifolia extract on cell viability and differentiation in mammary epithelial cells Fulltext Access 8 Pages 2008
Pharmacokinetics and immunomodulatory effects of phytotherapeutic lozenges (bonbons) with Echinacea purpurea extract Fulltext Access 8 Pages 2008
Berberine inhibits TPA-induced MMP-9 and IL-6 expression in normal human keratinocytes Fulltext Access 8 Pages 2008
20-Hydroxyecdysone increases fiber size in a muscle-specific fashion in rat Fulltext Access 8 Pages 2008
Increased sensitivity to bleomycin in upper aerodigestive tract mucosa of head and neck squamous cell carcinoma patients Fulltext Access 8 Pages 2008
Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: A randomized, double blind placebo controlled trial Fulltext Access 8 Pages 2008
In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes Fulltext Access 8 Pages 2008
Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells Fulltext Access 8 Pages 2008
Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin Fulltext Access 8 Pages 2008
Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine Fulltext Access 8 Pages 2008
Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism Fulltext Access 8 Pages 2008
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats Fulltext Access 8 Pages 2008
Ameliorative prospective of alpha-mangostin, a xanthone derivative from Garcinia mangostana against β-adrenergic cathecolamine-induced myocardial toxicity and anomalous cardiac TNF-α and COX-2 expressions in rats Fulltext Access 8 Pages 2008
Choice of cardiac tissue in vitro plays an important role in assessing the risk of drug-induced cardiac arrhythmias in human: Beyond QT prolongation Fulltext Access 8 Pages 2008
Comparison of different pharmacodynamic models for PK–PD modeling of verapamil in renovascular hypertension Fulltext Access 8 Pages 2008
Temporal variability of QT interval and changes in T wave morphology in dogs as markers of the clinical risk of drug-induced proarrhythmia Fulltext Access 8 Pages 2008
How many ECG leads are required for in vivo studies in safety pharmacology? Fulltext Access 8 Pages 2008
Organ weights and blood flows of sheep and pig for physiological pharmacokinetic modelling Fulltext Access 8 Pages 2008
The intravenous glucose tolerance test in cannulated Wistar rats: A robust method for the in vivo assessment of glucose-stimulated insulin secretion Fulltext Access 8 Pages 2008
Evaluation of Equine Laminar Vein Function: Harvesting, dissection and the use of functional methods to distinguish between veins and arteries Fulltext Access 8 Pages 2008
Zebrafish assays as early safety pharmacology screens: Paradigm shift or red herring? Fulltext Access 8 Pages 2008
Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: A biochemical and histoarchitectural evaluation Fulltext Access 8 Pages 2008
Pathophysiological effects of Androctonus australis hector scorpion venom: Tissue damages and inflammatory response Fulltext Access 8 Pages 2008
Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells Fulltext Access 8 Pages 2008
Comparison of primary lung tumor incidences in the rat evaluated by the standard microscopy method and by multiple step sections Fulltext Access 8 Pages 2008
Expression of neurotrophic factors in human primary pterygeal tissue and selective TNF-α-induced stimulation of ciliary neurotrophic factor in pterygeal fibroblasts Fulltext Access 8 Pages 2008
Modulation of cell growth and PPARγ expression in human colorectal cancer cell lines by ciglitazone Fulltext Access 8 Pages 2008
Inhibition on LS-174T cell growth and activity of telomerase in vitro and in vivo by arsenic trioxide Fulltext Access 8 Pages 2008
Ketoconazole-induced testicular damage in rats reduced by Gentiana extract Fulltext Access 8 Pages 2008
Cerebral vacuolation induced in rats by the administration of LUP-3FDC, an anti-tuberculosis cocktail Fulltext Access 8 Pages 2008
Differentially expressed pro- and anti-apoptogenic genes in response to benzene exposure: Immunohistochemical localization of p53, Bag, Bad, Bax, Bcl-2, and Bcl-w in lung epithelia Fulltext Access 8 Pages 2008
Global recognition of qualified toxicologic pathologists: Where we are now and where we need to go Fulltext Access 8 Pages 2008
Pelargonium sidoides for acute bronchitis: A systematic review and meta-analysis Fulltext Access 8 Pages 2008
The effect of trans-ferulic acid and gamma-oryzanol on ethanol-induced liver injury in C57BL mouse Fulltext Access 8 Pages 2008
Arsenic-induced health effects and genetic damage in keratotic individuals: Involvement of p53 arginine variant and chromosomal aberrations in arsenic susceptibility Fulltext Access 8 Pages 2008
Lack of genotoxic effects in hematopoietic and gastrointestinal cells of mice receiving chromium(VI) with the drinking water Fulltext Access 8 Pages 2008
Stimulatory effect of Crocus sativus (saffron) on β2-adrenoceptors of guinea pig tracheal chains Fulltext Access 8 Pages 2008
DNA damage in blood leukocytes of individuals with sickle cell disease treated with hydroxyurea Fulltext Access 8 Pages 2008
Temporal variation in the genotoxic potential of urban air particulate matter Fulltext Access 8 Pages 2008
Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders Fulltext Access 8 Pages 2008
Novel leads from Heliotropium ovalifolium, 4,7,8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5,7-dimethoxy-naphthalene-2-carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes Fulltext Access 8 Pages 2008
Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system Fulltext Access 8 Pages 2008
Modulation of gamma-ray-induced apoptosis in human peripheral blood leukocytes by famotidine and vitamin C Fulltext Access 8 Pages 2008
Depletion of WRN enhances DNA damage in HeLa cells exposed to the benzene metabolite, hydroquinone Fulltext Access 8 Pages 2008
Hypocholesterolemic effect of stilbenes containing extract-fraction from Cajanus cajan L. on diet-induced hypercholesterolemia in mice Fulltext Access 8 Pages 2008
Cancer chemopreventive activity of “rosin” constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test Fulltext Access 8 Pages 2008
The nitroxide antioxidant Tempol affects metal-induced cyto- and genotoxicity in human lymphocytes in vitro Fulltext Access 8 Pages 2008
Quantification of DNA repair capacity in whole blood of patients with head and neck cancer and healthy donors by comet assay Fulltext Access 8 Pages 2008
Differential DNA damage induced by H2O2 and bleomycin in subpopulations of human white blood cells Fulltext Access 8 Pages 2008
Taspine isolated from Radix et Rhizoma Leonticis inhibits growth of human umbilical vein endothelial cell (HUVEC) by inducing its apoptosis Fulltext Access 8 Pages 2008
Identification of a new mutagen, 4,4′-diamino-3,3′-dichloro-5-nitrobiphenyl, in river water flowing through an industrial area in Wakayama, Japan Fulltext Access 8 Pages 2008
Comparative study of Rhodiola preparations on behavioral despair of rats Fulltext Access 8 Pages 2008
Unexpected DNA damage caused by polycyclic aromatic hydrocarbons under standard laboratory conditions Fulltext Access 8 Pages 2008
Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology Fulltext Access 8 Pages 2008
Biomonitoring of DNA damage in peripheral blood lymphocytes of subjects with dental restorative fillings Fulltext Access 8 Pages 2008
Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation Fulltext Access 8 Pages 2008
Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX Fulltext Access 8 Pages 2008
Caiman latirostris (broad-snouted caiman) as a sentinel organism for genotoxic monitoring: Basal values determination of micronucleus and comet assay Fulltext Access 8 Pages 2008
Evaluation of the effects of the herbal product Catuama® in inflammatory and neuropathic models of nociception in rats Fulltext Access 8 Pages 2008
The gastric ulcer protective and healing role of cysteine proteinases from Carica candamarcensis Fulltext Access 8 Pages 2008
Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold Fulltext Access 8 Pages 2008
Anti-acids lead to immunological and morphological changes in the intestine of BALB/c mice similar to human food allergy Fulltext Access 9 Pages 2008
Histological alterations in ovaries of pubertal female rats induced by triphenyltin Fulltext Access 9 Pages 2008
Mast cell inhibition by ketotifen reduces splanchnic inflammatory response in a portal hypertension model in rats Fulltext Access 9 Pages 2008
Cytotoxicity of the β-carboline alkaloids harmine and harmaline in human cell assays in vitro Fulltext Access 9 Pages 2008
Neuroendocrine disorders in adult rats treated prenatally with hydrocortisone acetate Fulltext Access 9 Pages 2008
Inhalation toxicity studies: OECD guidelines in relation to REACH and scientific developments Fulltext Access 9 Pages 2008
A mannose-binding lectin from Sophora flavescens induces apoptosis in HeLa cells Fulltext Access 9 Pages 2008
Changes in antioxidant defense status in hypercholesterolemic rats treated with Ajuga iva Fulltext Access 9 Pages 2008
Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled study Fulltext Access 9 Pages 2008
Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis Fulltext Access 9 Pages 2008
Comparative in vitro study on the anti-herpetic effect of phytochemically characterized aqueous and ethanolic extracts of Salvia officinalis grown at two different locations Fulltext Access 9 Pages 2008
Chemoprofile and bioactivities of Taverniera cuneifolia (Roth) Arn.: A wild relative and possible substitute of Glycyrrhiza glabra L. Fulltext Access 9 Pages 2008
Differential protein expression in mouse splenic mononuclear cells treated with polysaccharides from spores of Ganoderma lucidum Fulltext Access 9 Pages 2008
A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs Oldenlandia diffusa and O. corymbosa and a new valuation of their biological potential Fulltext Access 9 Pages 2008
Effects of aqueous hop (Humulus Lupulus L.) extract on vascular reactivity in rats: Mechanisms and influence of gender and hormonal status Fulltext Access 9 Pages 2008
Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E Fulltext Access 9 Pages 2008
Protective effect of a standardized Ginkgo extract (ginaton) on renal ischemia/reperfusion injury via suppressing the activation of JNK signal pathway Fulltext Access 9 Pages 2008
The effect of Camphor–Crataegus berry extract combination on blood pressure and mental functions in chronic hypotension – A randomized placebo controlled double blind design Fulltext Access 9 Pages 2008
Effect of Ninjin-yoei-to (Rensheng-Yangrong-Tang) on olfactory behavior after olfactory nerve transection Fulltext Access 9 Pages 2008
Administration of ciprofibrate to lactating mothers induces PPARα-signaling pathway in the liver and kidney of suckling rats Fulltext Access 9 Pages 2008
Tetracycline-induced reproductive toxicity in male rats: Effects of vitamin C and N-acetylcysteine Fulltext Access 9 Pages 2008
In vitro models for the assessment of inflammatory and immuno-modulatory effects of the volatile organic compound chlorobenzene Fulltext Access 9 Pages 2008
Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment) Fulltext Access 9 Pages 2008
Acetaminophen-induced liver damage in mice: Effects of some medicinal plants on the oxidative defense system Fulltext Access 9 Pages 2008
Cyclic strain induces FosB and initiates osteogenic differentiation of mesenchymal cells Fulltext Access 9 Pages 2008