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Daneshyari Toxicology Journas Latest Articles

Toxicology Research Articles

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on molar and mandible traits in congenic mice: A test of the role of the Ahr locus
Fulltext Access 11 Pages 2007
Particle size-dependent radical generation from wildland fire smoke
Fulltext Access 11 Pages 2007
The novel histone deacetylase inhibitor 4-Me2N-BAVAH differentially affects cell junctions between primary hepatocytes
Fulltext Access 11 Pages 2007
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
Fulltext Access 11 Pages 2007
Changes in expression of fibrotic markers and histopathological alterations in kidneys of mice chronically exposed to low and high Cd doses
Fulltext Access 11 Pages 2007
Prolonged inflammatory gene response following soman-induced seizures in mice
Fulltext Access 11 Pages 2007
Distortion product otoacoustic emissions as non-invasive biomarkers and predictors of soman-induced central neurotoxicity: A preliminary study
Fulltext Access 11 Pages 2007
Different mechanisms of modulation of gap junction communication by non-genotoxic carcinogens in rat liver in vivo
Fulltext Access 11 Pages 2007
Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study
Fulltext Access 11 Pages 2007
An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: The protective role of some antioxidants
Fulltext Access 11 Pages 2007
Protective effect of benzothiazole derivative KHG21834 on amyloid β-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons
Fulltext Access 11 Pages 2007
Interaction between caspase-8 activation and endoplasmic reticulum stress in glycochenodeoxycholic acid-induced apoptotic HepG2 cells
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Developmental exposure to low-dose PBDE-99: Tissue distribution and thyroid hormone levels
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In vivo hydroquinone exposure impairs allergic lung inflammation in rats
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Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
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Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis
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Epigenetic gene regulation: Linking early developmental environment to adult disease
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Effect of bisphenol A on human chorionic gonadotrophin-stimulated gene expression of cultured mouse Leydig tumour cells
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A retrospective analysis of the added value of the rat two-generation reproductive toxicity study versus the rat subchronic toxicity study
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Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathy
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A new paradigm in toxicology and teratology: Altering gene activity in the absence of DNA sequence variation
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Maternal care, the epigenome and phenotypic differences in behavior
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In utero exposure to tributyltin chloride differentially alters male and female fetal gonad morphology and gene expression profiles in the Sprague–Dawley rat
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Developmental and reproductive toxicity evaluation of toluene vapor in the rat: II. Developmental toxicity
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Preclinical safety of recombinant human thrombin
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The Nrf2 transcription factor contributes to the induction of alpha-class GST isoenzymes in liver of acute cadmium or manganese intoxicated rats: Comparison with the toxic effect on NAD(P)H:quinone reductase
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Antioxidative and oxidative changes in the digestive gland cells of freshwater mussels Unio tumidus caused by selected phenolic compounds in the presence of H2O2 or Cu2+ ions
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Opercular epithelial cells: A simple approach for in vitro studies of cellular responses in fish
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Ellagic acid, a natural polyphenol protects rat peripheral blood lymphocytes against nicotine-induced cellular and DNA damage in vitro: With the comparison of N-acetylcysteine
Fulltext Access 11 Pages 2007
Preventive effect of naringin on cardiac markers, electrocardiographic patterns and lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats
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Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice
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Simulation of cholinesterase status at different scenarios of nerve agent exposure
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Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults
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Dopaminergic toxicity of the herbicide atrazine in rat striatal slices
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Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture
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Effect of acetaminophen administration to rats chronically exposed to depleted uranium
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In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity
Fulltext Access 11 Pages 2007
Oxidatively damaged DNA and inflammation in the liver of dyslipidemic ApoE−/− mice exposed to diesel exhaust particles
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Compositional assessment of event DAS-59122-7 maize using substantial equivalence
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A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes
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Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice
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DNA damage and p53 in RAW264.7 cells induced by the spores of co-cultivated Streptomyces californicus and Stachybotrys chartarum
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Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation
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Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats
Fulltext Access 11 Pages 2007
Reversal of lindane-induced impairment of step-down passive avoidance and oxidative stress by neurosteroids in rats
Fulltext Access 11 Pages 2007
Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
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Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture
Fulltext Access 11 Pages 2007
Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage
Fulltext Access 11 Pages 2007
Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans
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Preliminary morphological and morphometric study of rat cerebellum following sodium arsenite exposure during rapid brain growth (RBG) period
Fulltext Access 11 Pages 2007
Acrylamide effects on kinesin-related proteins of the mitotic/meiotic spindle
Fulltext Access 11 Pages 2007
Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats
Fulltext Access 11 Pages 2007
Differential surface expression of CD18 and CD44 by neutrophils in bone marrow and spleen contributed to the neutrophilia in thalidomide-treated female B6C3F1 mice
Fulltext Access 11 Pages 2007
Pancreatic cancer: Pathogenesis, prevention and treatment
Fulltext Access 11 Pages 2007
Tissue- and cell-specific expression of metallothionein genes in cadmium- and copper-exposed mussels analyzed by in situ hybridization and RT–PCR
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Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus
Fulltext Access 11 Pages 2007
ERK-dependent and -independent pathways trigger human neural progenitor cell migration
Fulltext Access 11 Pages 2007
Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol
Fulltext Access 11 Pages 2007
Glutathione regulation of redox-sensitive signals in tumor necrosis factor-α-induced vascular endothelial dysfunction
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Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53
Fulltext Access 11 Pages 2007
Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression
Fulltext Access 11 Pages 2007
Dendritic cells and skin sensitization: Biological roles and uses in hazard identification
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Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder
Fulltext Access 11 Pages 2007
Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice
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Lead effects on development and function of bone marrow-derived dendritic cells promote Th2 immune responses
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Research toward the development of a biologically based dose response assessment for inorganic arsenic carcinogenicity: A progress report
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Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells
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Brain regional acetylcholinesterase activity and muscarinic acetylcholine receptors in rats after repeated administration of cholinesterase inhibitors and its withdrawal
Fulltext Access 11 Pages 2007
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate
Fulltext Access 11 Pages 2007
Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: Role of the specific surface area and of surface methylation of the particles
Fulltext Access 11 Pages 2007
Corepressors of agonist-bound nuclear receptors
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Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration
Fulltext Access 11 Pages 2007
Urine acidification has no effect on peroxisome proliferator-activated receptor (PPAR) signaling or epidermal growth factor (EGF) expression in rat urinary bladder urothelium
Fulltext Access 11 Pages 2007
Methamphetamine and 3,4-methylenedioxymethamphetamine interact with central nicotinic receptors and induce their up-regulation
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A role for transforming growth factor-β apoptotic signaling pathway in liver injury induced by ingestion of water contaminated with high levels of Cr(VI)
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Safety assessment of hydroxypropyl methylcellulose as a food ingredient
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Intravenous repeated-dose toxicity study of ZnPcS2P2-based-photodynamic therapy in beagle dogs
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A mechanism-based cancer risk assessment for 1,4-dichlorobenzene
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Monitoring liver safety in drug development: The GSK experience
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Studies on the non-pathogenicity of Chryseobacterium proteolyticum and on the safety of the enzyme: Protein–glutaminase
Fulltext Access 11 Pages 2007
A comparative study of the mutagenicity of various types of tobacco products
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Impact of a risk-benefit advisory on fish consumption and dietary exposure to methylmercury in France
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Review of the in vitro and in vivo genotoxicity of dichlorvos
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One-generation reproductive toxicity study of DHA-rich oil in rats
Fulltext Access 11 Pages 2007
Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models
Fulltext Access 11 Pages 2007
P3 components and adolescent binge drinking in Southwest California Indians
Fulltext Access 11 Pages 2007
The relation of low-level prenatal lead exposure to behavioral indicators of attention in Inuit infants in Arctic Quebec
Fulltext Access 11 Pages 2007
Prenatal methylmercury exposure increases responding under clocked and unclocked fixed interval schedules of reinforcement
Fulltext Access 11 Pages 2007
Isoflavonoid-based bone-sparing treatments exert a low activity on reproductive organs and on hepatic metabolism of estradiol in ovariectomized rats
Fulltext Access 11 Pages 2007
A 90-day safety study of genetically modified rice expressing Cry1Ab protein (Bacillus thuringiensis toxin) in Wistar rats
Fulltext Access 11 Pages 2007
Hazard characterisation in food allergen risk assessment: The application of statistical approaches and the use of clinical data
Fulltext Access 11 Pages 2007
A probabilistic model for simultaneous exposure to multiple compounds from food and its use for risk–benefit assessment
Fulltext Access 11 Pages 2007
Bioscreening of Australian olive mill waste extracts: Biophenol content, antioxidant, antimicrobial and molluscicidal activities
Fulltext Access 11 Pages 2007
Direct effects of manganese compounds on dopamine and its metabolite Dopac: An in vitro study
Fulltext Access 11 Pages 2007
Immunoassays for avian butyrylcholinesterase: Implications for ecotoxicological testing and clinical biomonitoring
Fulltext Access 11 Pages 2007
Copper modifies liver microsomal UDP-glucuronyltransferase activity through different and opposite mechanisms
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Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
Fulltext Access 11 Pages 2007
Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione
Fulltext Access 11 Pages 2007
Synaptic contacts impaired by styrene-7,8-oxide toxicity
Fulltext Access 11 Pages 2007
Genistein genotoxicity: Critical considerations of in vitro exposure dose
Fulltext Access 11 Pages 2007
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