Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11030829 | Trends in Food Science & Technology | 2018 | 25 Pages |
Abstract
Changing the gut microbiota by diet is possible, but an assessment of the impact on CMH risk is still needed, including clarifying advantages above other known dietary routes. The individual gut microbiota composition may in part determine the impact of diet and its effects on health. Therefore, future developments may identify individuals at risk and thus possible modification of the microbiota to achieve benefits in susceptible (sub) populations depending on their initial microbiota composition. Prebiotics currently appear to be the most promising ingredients; however, required doses may be relatively high and the actual role of gut microbiota needs further assessment. Overall, causal evidence linking gut microbiota interventions with CMH benefits are developing in preclinical models but are still lacking in humans. A significant research effort is needed and ongoing to determine whether potential effects can be reliably substantiated.
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Authors
Elke A. Trautwein, Harry P.F. Peters, David J. Mela, Christine Edwards, Hilde Herrema, Jingyuan Fu, Marian Geldof, Ruud Albers,