| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2019327 | Progress in Lipid Research | 2006 | 13 Pages |
Abstract
In this review, we will present and discuss the regulation of the mammalian fatty acid elongases and their potential role in lipid metabolism. We will consider both the biochemical functions of the proteins, as well as their role in a more physiological context.
Keywords
EPAFIAFELOELOVLFAEDGATSREBPLXRPPARBATSSCHEKPEAFASNADPHACCSCDacetyl-CoA carboxylaseEicosapentaenoic aciddocosahexaenoic acidPolyunsaturated fatty acidsfatty acid synthasePUFAFatty acid elongasebrown adipose tissueTERCNSDHADiacylglycerol acyltransferasehuman embryonic kidney cellscentral nervous systemFaceNADHnicotinamide adenine dinucleotide phosphateNAD, nicotinamide adenine dinucleotidesterol regulatory element binding proteinKarliver X receptorperoxisome proliferator-activated receptor
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Authors
Andreas Jakobsson, Rolf Westerberg, Anders Jacobsson,