| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2079780 | Current Opinion in Food Science | 2015 | 6 Pages |
•We reviewed the influence of engineered nanoparticles on nutraceuticals bioaccessibility.•We reviewed the influence of engineered nanoparticles on nutraceuticals absorption.•We reviewed the influence of engineered nanoparticles on nutraceuticals metabolism.
Many important nutraceuticals have poor oral bioavailability, which greatly lowers their efficacy as health-promoting agents. Engineered nanoparticles (ENs) can be used to fabricate delivery systems that improve oral bioavailability through a number of mechanisms: increasing nutraceutical stability in foods and the gastrointestinal tract (GIT); enhancing nutraceutical solubility in intestinal fluids; facilitating nutraceutical absorption by GIT; and decreasing first-pass metabolism in the gut and liver. This review depicts the mode of actions of different food-grade ENs in improving oral bioavailability of nutraceuticals.
