| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2587962 | Food and Chemical Toxicology | 2006 | 7 Pages |
Abstract
Immunohistochemistry and immunoelectron microscopy showed that FLUT depressed cortactin expression in the apical ES. In addition, the effect of FLUT on cortactin localization appeared between 12Â h and 8Â days (about 180Â h) after a one-day treatment. These results suggest that FLUT depressed the expression of cortactin in the apical ES with stage specificity. Therefore, the initial target of FLUT may be the cell-cell interactions between the Sertoli and germ cells. To our knowledge, this study is the first to document the decrease of cortactin expression in the abnormal apical ES following treatment with FLUT.
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Authors
Reiko Anahara, Yoshiro Toyama, Mamiko Maekawa, Masayuki Kai, Fumitoshi Ishino, Kiyotaka Toshimori, Chisato Mori,