Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2653807 | Journal of the American Dietetic Association | 2011 | 10 Pages |
BackgroundMicronutrient deficiencies have been associated with an increase in fat deposition and body weight; thus, adding them to low-fat milk may facilitate weight loss when accompanied by an energy-restricted diet.ObjectiveThe objective was to evaluate the effect of the intake of low-fat milk and low-fat milk with added micronutrients on anthropometrics, body composition, blood glucose levels, lipids profile, C-reactive protein, and blood pressure of women following an energy-restricted diet.DesignA 16-week randomized, controlled intervention study.Participants/settingsOne hundred thirty-nine obese women (aged 34±6 years) from five rural communities in Querétaro, Mexico.InterventionWomen followed an energy-restricted diet (−500 kcal) and received in addition one of the following treatments: 250 mL of low-fat milk (LFM) three times/day, 250 mL of low-fat milk with micronutrients (LFM+M) three times/day, or a no milk control group (CON). Weight, height, and hip and waist circumferences were measured at baseline and every 4 weeks. Body composition measured by dual-energy x-ray absorptiometry, blood pressure, and blood analysis were done at baseline and at the end of the 16 weeks.Main outcome measuresChanges in weight and body composition.Statistical analysisOne-factor analysis of variance, adjusted by age, baseline values, and community random effects.ResultsAfter the 16-week intervention, participants in the LFM+M group lost significantly more weight (−5.1 kg; 95% CI: −6.2 to −4.1) compared with LFM (−3.6 kg; 95% CI: −4.7 to −2.6) and CON (−3.2 kg; 95% CI: −4.3 to −2.2) group members (P=0.035). Body mass index change in the LFM+M group (−2.3; 95% CI: −2.7 to −1.8) was significantly greater than LFM group members (−1.5; 95% CI: −2.0 to −1.1) and CON group members (−1.4; 95% CI: −1.9 to −0.9) (P=0.022). Change in percent body fat among LFM+M group members (−2.7%; 95% CI: −3.2 to −2.1) was significantly higher than LFM group members (−1.8%; 95% CI: −2.3 to −1.3) and CON group members (−1.6%; 95% CI: −2.2 to −1.0) (P=0.019). Change in bone mineral content was significantly higher in LFM group members (29 mg; 95% CI: 15 to 44) and LFM+M group members (27 mg; 95% CI: 13 to 41) compared with CON group members (−2 mg; 95% CI: −17 to −14) (P=0.007). No differences were found between groups in glucose level, blood lipid profile, C-reactive protein level, or blood pressure.ConclusionsIntake of LFM+M increases the effectiveness of an energy-restricted diet to treat obesity, but had no effect on blood lipid levels, glucose levels, C-reactive protein, or blood pressure.