| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5551068 | Journal of Food and Drug Analysis | 2017 | 10 Pages |
â¢Chemical structures and pharmacological benefits of capsaicinoids have been reviewed.â¢Extraction methods for capsaicinoids from fresh and dried pepper fruits are listed and compared.â¢Bioavailabilities of capsaicinoids are discussed in terms of absorption, distribution, metabolism and elimination.
Capsaicinoids are active constituents responsible for the pungent and spicy flavor in chili peppers. During the past few decades, various extraction methods of capsaicinoids from peppers have been developed with high yields. Through biological studies, pharmacological benefits have been reported such as pain relief, antiinflammation, anticancer, cardio-protection, as well as weight loss. In this paper, the extraction methods and bioavailability of capsaicinoids are reviewed and discussed. In addition, the pharmacological effects and their underlying mechanisms are also studied.
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