Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5559982 | Food and Chemical Toxicology | 2017 | 12 Pages |
Abstract
We have found dependence of cell damage on concentrations of MeO-NPs and higher cytotoxicity of Mn3O4-NP compared with NiO-NP. Thus, comparative assessment of the NPs unspecific toxicity obtained in our animal experiments was reproduced by the “in vitro” tests. However, with respect to manganese-specific brain damage “in vivo” discovered previously, present experiments on neurons “in vitro” showed only a certain enhancing effect of Mn3O4-NP on the action of NiO-NP, but the role of NiO-NP in the combination prevailed.
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Authors
Ilzira Minigalieva, Tatiana Bushueva, Eleonore Fröhlich, Claudia Meindl, Kristin Ãhlinger, Vladimir Panov, Anatoly Varaksin, Vladimir Shur, Ekaterina Shishkina, Vladimir GurviÑh, Boris Katsnelson,