Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5849607 | Food and Chemical Toxicology | 2015 | 8 Pages |
Abstract
Our data support the involvement of the COX-2 and 5-LOX genes in liver metabolism of OTA. On the basis of the gene expression analysis, the results suggest a possible impairment in OTA secretion at the intestinal and hepatic level due to MRP2 repression. In addition, we provide evidence of the effect of OTA on NAT2 gene expression, which had not been reported before.
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Authors
C.A. González-Arias, A. Crespo-Sempere, S. MarÃn, V. Sanchis, A.J. Ramos,