| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5850433 | Food and Chemical Toxicology | 2013 | 10 Pages |
Abstract
- Laurus nobilis leaf CHCl3 extract and the fractions derived therefrom are in the focus of the study.
- A GC-EI-MS metabolic profiling analysis was performed.
- Cytotoxicity vs. neuronal (SK-N-BE(2)-C, SH-SY5Y) and glial (C6) cell lines were evaluated.
- Apoptosis was assessed by caspase-3 activation and DNA fragmentation assays.
- Cytotoxic extracts showed a strong OH oxidant ability.
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Authors
Severina Pacifico, Marialuisa Gallicchio, Peter Lorenz, Nicoletta Potenza, Silvia Galasso, Sabina Marciano, Antonio Fiorentino, Florian C. Stintzing, Pietro Monaco,