| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5850857 | Food and Chemical Toxicology | 2014 | 16 Pages |
Abstract
- Crocin is of benefit to CNS and cardiovascular systems.
- At pharmacological doses it does not harm liver and other organs' function.
- ROS Suppression seems to be the underlying mechanism by which crocin exerts its therapeutic effects.
Keywords
Crocus sativus L.TLCGSHIC50i.c.v.TBAPTZi.pMMSintracerebroventricularTBARSCPPFAB-MSMDATNFAMDnuclear magnetic resonanceCrocinROSfast atom bombardment-mass spectrometryToxicological effectsSpiceBioactivitiesischemia-reperfusionconditioned place preferencetriglycerideNMRMaximal electroshock seizureintraperitonealSaffronSODage-related macular degenerationSuperoxide dismutasetumor necrosis factorlactate dehydrogenaseLDHmalondialdehydeultraviolet/visiblemethyl methanesulfonateMeSNitric oxidehalf maximal inhibitory concentrationPentylenetetrazoleCreatine kinasethin layer chromatographyhigh performance liquid chromatographyHPLCGas chromatographyglutathione peroxidasethiobarbituric acid reactive speciesReactive oxygen species
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Authors
Seyedeh Hoda Alavizadeh, Hossein Hosseinzadeh,