Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5850859 | Food and Chemical Toxicology | 2014 | 9 Pages |
Abstract
In conclusion, endosulfan decreases rat testes weight, and inhibits spermatogenesis and steroidogenesis. It induces oxidative stress and apoptosis by possible mechanisms of both mitochondria and non-mitochondria pathways. These data provide insight into the mode of action of endosulfan-induced toxicity and the beneficial role provided by taurine to counteract endosulfan-induced oxidative stress and apoptosis in rat testis.
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Authors
Hamdy A.A. Aly, Rasha M. Khafagy,