Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5851386 | Food and Chemical Toxicology | 2013 | 7 Pages |
Abstract
⺠Oleuropein is toxic against different breast cancer cell lines. ⺠Oleuropein triggers apoptosis efficiently in ER-negative MDA-MB-231 cells. ⺠The intrinsic pathway is involved in the apoptosis process. ⺠Oleuropein delays the cell cycle of breast cancer cells at S phase. ⺠Oleuropein down-regulates NF-κB and its main oncogenic target cyclin D1.
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Authors
Maha H. Elamin, Maha H. Daghestani, Sawsan A. Omer, Mai A Elobeid, Promy Virk, Ebtesam M. Al-Olayan, Zeinab K. Hassan, Osama B. Mohammed, Abdelilah Aboussekhra,