Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5851464 | Food and Chemical Toxicology | 2013 | 11 Pages |
Abstract
⺠The acetaminophen hepatotoxicity model is most popular for natural product testing. ⺠Pitfalls of the model make the interpretation of natural product studies difficult. ⺠Fundamental aspects of the model need to be considered for sound data interpretation. ⺠Goal is to enable researcher to select the appropriate experimental design and model. ⺠This yields clinically relevant and mechanistically valid data for natural products.
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Food Science
Authors
Hartmut Jaeschke, C. David Williams, Mitchell R. McGill, Yuchao Xie, Anup Ramachandran,