| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5851508 | Food and Chemical Toxicology | 2013 | 8 Pages |
Abstract
⺠Human intestinal transport of F was studied, using the Caco-2 cell line as a model of the intestinal epithelium. ⺠F absorption is moderate (<70%) in absorptive (apical-basolateral) and secretory (basolateral-apical) directions. ⺠In both absorptive and secretory directions, F is transported by paracellular pathway, which may be considered predominant. ⺠Non-ionized state, participation of Fâ/H+ cotransporter or Fâ/OHâ antiporter may explain why transport increases at acid pH. ⺠Possible transcellular participation of mechanisms involved in transport of Clâ and active transport in secretory direction.
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Authors
R.A. Rocha, V. Devesa, D. Vélez,