| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5851894 | Food and Chemical Toxicology | 2013 | 6 Pages |
Abstract
⺠The effects of artemisinic acid on melanogenesis were investigated. ⺠Artemisinic acid reduced melanin content and mRNA levels of MITF, tyrosinase, TRP-1 and TRP-2. ⺠Artemisinic acid inhibited cholesterol synthesis through downregulation of the HMG CoA reductase gene. ⺠Downregulation of the HMG CoA reductase gene by artemisinic acid was mediated through reduced expression of the C/EBP α gene.
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Authors
Jongsung Lee, Jienny Lee, Eunsun Jung, Jae Youl Cho, Deokhoon Park,