| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5851976 | Food and Chemical Toxicology | 2013 | 7 Pages |
Abstract
⺠Acrylamide caused mitochondria collapse and apoptosis. ⺠Cell apoptosis was activated under the exposure to 2 mM acrylamide but not less than 1 mM. ⺠The ultrastructure alterations of mitochondria showed chromatin condensation, pyknosis, and swelling after acrylamide treatment.
Keywords
MMPPARPBERACR2,7-dichlorodihydrofluorescein diacetate3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromideDMSOMTTROSAcrylamideTembase excision repairminimum essential mediumApoptosisDimethyl sulfoxidebovine serum Astrocytoma cellsMEMTransmission electron microscopeMitochondria membrane potentialPoly(ADP-ribose) polymeraseReactive oxygen species
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Authors
Jong-Hang Chen, Cheng-Hsien Yang, Yan-Shiu Wang, Jiann-Gwu Lee, Chiung-Hsiang Cheng, Chin-Cheng Chou,