| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852011 | Food and Chemical Toxicology | 2012 | 8 Pages |
Abstract
⺠Comparison between edible (PGJ) and non-edible (PGME) parts of pomegranate fruit. ⺠PGME exhibited much greater polyphenol content and antimicrobial activity than PGJ. ⺠First time demonstration: enhancement of ciprofloxacin activity by PGME. ⺠Ciprofloxacin-PGME combination is synergic against ESBL and MBL producing bacteria. ⺠A cost-effective way to combat global emergence of multi-drug resistant bacteria.
Keywords
EGCGMBLESBLEPIATCCCLSIFICMetallo-β-lactamase (MBL)GAEMHAMFPMICPGMEOMFSDAONPGExtended-spectrum β-lactamase (ESBL)TSIRNDSabouraud dextrose agarPGJCFUMDRDMSOMHbExtended-spectrum β-lactamaseEDTAethylenediaminetetraacetateortho-nitrophenyl-β-galactosideepigallocatechin gallateELISAEnzyme-linked immunosorbent assayMinimum inhibitory concentrationDimethyl sulfoxideCiprofloxacinfractional inhibitory concentrationMetallo-β-lactamaseAmerican Type Culture CollectionPolyphenol contentGallic acid equivalentquercetin equivalentMulti drug resistanceresistance-nodulation-divisionEfflux pump inhibitorClinical and Laboratory Standards InstituteAntimicrobial synergyoptical densitycolony forming unit
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Authors
Diganta Dey, Sukalyani Debnath, Sudipta Hazra, Subhalakshmi Ghosh, Ratnamala Ray, Banasri Hazra,