Article ID Journal Published Year Pages File Type
5852028 Food and Chemical Toxicology 2012 7 Pages PDF
Abstract
► Anti-inflammatory activity of saucerneol D (SD) was evaluated using mast cells. ► SD dose-dependently inhibited generation of PGD2 and LTC4 as well as degranulation. ► SD suppressed Syk-mediated activation of PLCγ1, MAP kinases and NF-κB pathway. ► SD might be beneficial in regulating various allergic inflammatory reactions.
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Life Sciences Agricultural and Biological Sciences Food Science
Preview
Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells
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