| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852038 | Food and Chemical Toxicology | 2012 | 9 Pages |
Abstract
⺠We evaluated Canova effects on non-human primate treated with cyclophosphamide. ⺠Cyclophosphamide induced abnormal WBC count, micronucleus and DNA damage in all animals. ⺠Canova treated animals presented a higher leukocyte count than the animals without this treatment. ⺠Animals treated with Canova presented lower frequency of micronucleus and DNA damage than animals without this medicine. ⺠Canova treatment minimizes cyclophosphamide myelotoxicity in Cebus apella.
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Authors
Mariana Ferreira Leal, Lusânia Maria Greggi Antunes, Maria Fernanda Vita Lamarão, Carla Elvira Araújo da Silva, Ismael Dale Cotrim Guerreiro da Silva, Paulo Pimentel Assumpção, Edilson Ferreira Andrade, Alexandre Pingarilho Rezende,