| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852071 | Food and Chemical Toxicology | 2013 | 10 Pages |
Abstract
⺠Subchronic toxicity of Apoaequorin, a protein preparation was investigated in rats. ⺠Apoaequorin administration to rats at doses up to 667 mg/kg/day for 90 days did not reveal any adverse effects. ⺠The No Observed-Adverse-Effect Level (NOAEL) for Apoaequorin was determined as 667 mg/kg bw/day, the highest dose tested.
Keywords
FDANOAELSDHsorbitol dehydrogenaseALTALKPMCVMCHOECDASTAspartate aminotransferaseAlanine aminotransferaseAlkaline phosphataseSafetyMean corpuscular volumeBUNFood and Drug AdministrationOrganization for Economic Co-operation and DevelopmentToxicitymean corpuscular hemoglobinDietary supplementblood urea nitrogenno-observed-adverse-effect level
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Authors
Daniel L. Moran, Palma Ann Marone, Mark R. Bauter, Madhu G. Soni,