Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852179 | Food and Chemical Toxicology | 2012 | 7 Pages |
Abstract
⺠Naringenin induces HO-1 expression and activity in VSMCs. ⺠Naringenin inhibits TNF-α-induced VSMC proliferation, migration and ROS generation. ⺠Such inhibitory effects of naringenin are dependent on the HO-1 induction.
Keywords
DCF-DAHeme oxygenase-1VSMCSREBP-1cPAI-1ZnPPOPNERKMMP-9MAPKMTTROSOsteopontinProliferationtumor necrosis factor alphadichlorodihydrofluorescein diacetateVascular smooth muscle cellVascular smooth muscle cellsTNF-αMatrix metalloproteinase-9MigrationPlasminogen activator inhibitor-1Naringeninheme oxygenaseSterol regulatory element binding protein-1cmitogen-activated protein kinaseZinc protoporphyrinextracellular signal-regulated kinaseReactive oxygen species
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Authors
Siyu Chen, Yan Ding, Weiwei Tao, Wenxiang Zhang, Tingming Liang, Chang Liu,