Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852223 | Food and Chemical Toxicology | 2012 | 9 Pages |
Abstract
⺠Mechanism as well as the outcome of AE action against melanoma is defined by cell specificity. ⺠Induction of differentiation vs. apoptotic cell death is oppositely regulated by most important signals, ERK1/2 and Akt. ⺠Apoptotic cell death is triggered even in cells with permanently activated Akt. ⺠Independently from different intracellular response AE antagonized chemotherapy.
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Authors
J. Radovic, D. Maksimovic-Ivanic, G. Timotijevic, S. Popadic, Z. Ramic, V. Trajkovic, D. Miljkovic, S. Stosic-Grujicic, S. Mijatovic,