| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852232 | Food and Chemical Toxicology | 2012 | 7 Pages |
Abstract
⺠We investigate the toxicity of AFG1 in rat lung AT-II. ⺠AFG1 impairs lamellar bodies of AT-II and decreases SP-C expression in lung tissues. ⺠AFG1 decreased SP-C expression in AT-II in vitro. ⺠AFG1 induced a considerable rise of [Ca2+]i might contribute the decreased SP-C. ⺠AFG1 impairs structure and function of AT-II involved in the pulmonary toxicity.
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Authors
Haitao Shen, Ping Lv, Xin Xing, Lingxiao Xing, Xia Yan, Junling Wang, Xianghong Zhang,