Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852344 | Food and Chemical Toxicology | 2012 | 6 Pages |
Abstract
⺠Metabolism of parabens in MCF7 cells. ⺠Cytotoxicity of parabens increased with the alkyl chain. ⺠Parabens are stable in cultured MCF7 cells. ⺠Parabens did not undergo hydrolysis, conjugation to glucuronic acid or sulfate in MCF7 homogenates. ⺠Results may explain the accumulation of parabens in breast cancer tissue.
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Authors
Zeina Dagher, Mireille Borgie, Jacques Magdalou, Ramez Chahine, Hélène Greige-Gerges,