Anti-inflammatory activity of hydroxycinnamic acid derivatives isolated from corn bran in lipopolysaccharide-stimulated Raw 264.7 macrophages

Article ID	Journal	Published Year	Pages	File Type
5852424	Food and Chemical Toxicology	2012	8 Pages	PDF

Abstract

âº The EECB inhibited LPS-induced NO production and iNOS expression. âº DFP showed the most potent inhibition on NO production. âº The four HADs significantly reduced the LPS-induced increase in NF-ÎºB promoter activity. âº Phenolic amides in the corn bran may be a potential source of natural anti-inflammatory agents.

Keywords

PBS XTT DCP iNOS DFP CFP FBS LPS NF-κB p-Coumaric acid Phenolic amides Cinnamic acids Corn bran fetal bovine serum inducible nitric oxide synthase Nuclear factor-kappa B Ferulic acid Phosphate buffered saline lipopolysaccharide Nitric oxide HADS