| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852466 | Food and Chemical Toxicology | 2012 | 12 Pages |
Abstract
⺠Subchronic toxicity and genotoxicity of Irvingia gabonensis extract was investigated. ⺠No adverse effects of Irvingia gabonensis extract was noted in subchronic toxicity in rats at doses up to 2500 mg/kg/day. ⺠Irvingia gabonensis extract was not genotoxic as evaluated by in vitro and in vivo studies. ⺠The No Observed-Adverse-Effect Level (NOAEL) for Irvingia gabonensis extract was >2500 mg/kg/day.
Keywords
GGTFDAGLDHNOAELMCVMCHOECDALTMNPCEPCEmicronucleated polychromatic erythrocytesASTAspartate aminotransferaseAlanine aminotransferaseALPAlkaline phosphatasepolychromatic erythrocytesSafetyMean corpuscular volumeBUNFood and Drug AdministrationOrganization for Economic Co-operation and DevelopmentToxicitymean corpuscular hemoglobinDietary supplementblood urea nitrogenno-observed-adverse-effect levelGamma-glutamyl transferaseglutamate dehydrogenase
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Authors
Shil C. Kothari, Prasad Shivarudraiah, Suresh Babu Venkataramaiah, Swapna Gavara, Madhu G. Soni,