Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852479 | Food and Chemical Toxicology | 2012 | 5 Pages |
Abstract
⺠Ethanol extracts of 188 medicinal plants were screened for NF-κB inhibitory activity. ⺠Chrysanthemum indicum Linne extract (CIE) inhibits Epstein-Barr virus LMP1-induced NF-κB activation. ⺠CIE inhibits LMP1-induced NF-κB activation by blocking IKKα or IKKβ activation. ⺠CIE treatment selectively kills EBV transformed lymphoblastoid cell lines. ⺠CIE has potent inhibitory effect on EBV-transformed LCL viability.
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Authors
Jung-Eun Kim, Soojin Jun, Minji Song, Joo-Hwan Kim, Yoon-Jae Song,