Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852524 | Food and Chemical Toxicology | 2012 | 12 Pages |
Abstract
⺠Leaves decoction of Smallanthus sonchifolius (yacon) is a protective agent against renal damage during diabetes. ⺠Altered renal parameters were normalized in yacon decoction-treated diabetic rats. ⺠Yacon decoction alleviates early glomerulosclerosis in diabetes through TGF-β/Smad inhibition. ⺠The results might promote a better understanding for the molecular mechanisms of yacon decoction actions during diabetes.
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Authors
Stella M. Honoré, Wilfredo M. Cabrera, Susana B. Genta, Sara S. Sánchez,