Article ID Journal Published Year Pages File Type
5852572 Food and Chemical Toxicology 2012 10 Pages PDF
Abstract
► Mercury alone induced Cyp1a1/1a2/1b1 in the kidney but not in the lung and heart. ► Mercury potentiated the inducible Cyp1a1/1a2/1b1 at mRNA in the kidney. ► Mercury inhibited the inducible Cyp1a1/1a2/1b1 at protein and activity in the kidney. ► Mercury potentiated the inducible Cyp1a1/1a2/1b1 at mRNA and protein in the lung. ► Mercury potentiated the constitutive and inducible Nqo1, Gsta1 in all tissues.
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