Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852572 | Food and Chemical Toxicology | 2012 | 10 Pages |
Abstract
⺠Mercury alone induced Cyp1a1/1a2/1b1 in the kidney but not in the lung and heart. ⺠Mercury potentiated the inducible Cyp1a1/1a2/1b1 at mRNA in the kidney. ⺠Mercury inhibited the inducible Cyp1a1/1a2/1b1 at protein and activity in the kidney. ⺠Mercury potentiated the inducible Cyp1a1/1a2/1b1 at mRNA and protein in the lung. ⺠Mercury potentiated the constitutive and inducible Nqo1, Gsta1 in all tissues.
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Authors
Issa E.A. Amara, Anwar Anwar-Mohamed, Ghada Abdelhamid, Ayman O.S. El-Kadi,