Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852624 | Food and Chemical Toxicology | 2012 | 9 Pages |
Abstract
⺠Fibermalt is composed (⩾80%) of indigestible maltose alternan oligosaccharides. ⺠Fibermalt was nonmutagenic in a bacterial reverse mutation test. ⺠In a 13-week dietary study in rats, fibermalt was administered at up to 150,000 ppm. ⺠No fibermalt-related toxicity was noted in any of the treatment animals. ⺠The NOAEL for fibermalt is stated at 150,000 ppm, the highest dose evaluated.
Keywords
RDWALBGLPGRASRRVMCVWBCABASHCTPTTRBCALTNOAEL2-aminoanthraceneCPNALKPOECDsorbitol dehydrogenaseNaN3PLTCREA4-NOPDCHOLChronic progressive nephropathyFDAMAOSAILMMSMCHFOBMCHCAPTTmethylmethanesulfonateSDH2-AADMSOASTAspartate aminotransferaseAlanine aminotransferaseAlbuminAlkaline phosphataseFunctional observational batterygenerally recognized as safeBILIanalysis of varianceANOVAtrigTriglyceridestotal white blood cell countred blood cell countGood Laboratory PracticeMutagenicityMean corpuscular volumeBUNdegree of polymerizationDimethyl sulfoxideDietprothrombin timeFood and Drug AdministrationOrganisation for Economic Co-operation and DevelopmentSodiumsodium azideToxicityPlatelet countRed blood cell distribution widthHemoglobin concentrationInorganic phosphorusmean corpuscular hemoglobinRatMean corpuscular hemoglobin concentrationblood urea nitrogenhematocritHgbno observable adverse effect levelPotassiumcalglobtotal bilirubinTotal serum proteinChloridetotal cholesterolCalciumEuropean CommissionGlobulinGlucFasting glucose
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Authors
Laurie C. Dolan, Eva Gietl, Ursula La Cognata, Volker Landschütze, Palma Ann Marone, Ray A. Matulka,