Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852757 | Food and Chemical Toxicology | 2012 | 7 Pages |
Abstract
⺠Proanthocyanidins from Croton celtidifolius prevent human LDL oxidation. ⺠PRF protect endothelial cells from cytotoxic effects of oxidized LDL. ⺠PRF improve endothelial function in LDLrâ/â mice.
Keywords
GSSGCroton celtidifolius2′7′-dichlorodihydrofluorescein diacetateLDL receptor knockout miceoxLDLVCAM-1RNSDCFH-DAPHEICAM-1HUVECSGSHTrpHDLPRFLDLR−/−O2−ONOO−ROSAtherosclerosissuperoxide anionAChAcetylcholineTryptophanOxidative stressconjugated dienesHuman umbilical vein endothelial cellsEndothelial cellsTNF-αphenylephrinehigh density lipoproteinoxidized low density lipoproteinlow density lipoproteinLDLintercellular adhesion molecule-1Nitric oxideProanthocyanidinsVascular cell adhesion protein-1Peroxynitritereduced glutathioneMicellar electrokinetic chromatographytotal cholesteroloxidized glutathionereactive nitrogen speciesReactive oxygen species
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Agricultural and Biological Sciences
Food Science
Authors
Mariana Appel Hort, Marcos Raniel Straliotto, Mariana Silveira Duz, Paula Moro Netto, Christiane Borges Souza, Tamirys Schulz, Heros Horst, Moacir Geraldo Pizzolatti, Andreza Fabro de Bem, Rosa Maria Ribeiro-do-Valle,