| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852821 | Food and Chemical Toxicology | 2012 | 9 Pages |
Abstract
⺠Increased activation of Rho kinase was demonstrated in a rat model of streptozotocin-induced diabetes. ⺠Long-term administration of fasudil, a Rho kinase inhibitor, improved cardiac tissue damage of diabetes. ⺠Long-term administration of fasudil improved signs of diabetic cardiomyopathy.
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Authors
Sheng-jiang Guan, Zhi-hong Ma, Yan-ling Wu, Jian-ping Zhang, Feng Liang, J. Woodrow Weiss, Qian-yu Guo, Jiang-yan Wang, En-sheng Ji, Li Chu,