Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5852822 | Food and Chemical Toxicology | 2012 | 8 Pages |
Abstract
⺠Glucocorticoids and β-amyloid peptides deposition are correlated with AD. ⺠It is unclear about the simultaneous effects of glucocorticoids and Aβ on neurons. ⺠DEX + Aβ25-35 can accelerate learning and memory impairments, increase APP processing. ⺠AST treatment can improve the learning and memory and decrease APP and Aβ expression. ⺠AST has protective effects on hippocampus neuronal injury induced by GCs + Aβ.
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Authors
Wei-Zu Li, Wang-Yang Wu, Da-Ke Huang, Yan-Yan Yin, Hong-Wei Kan, Xin Wang, Yu-You Yao, Wei-Ping Li,