| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5852910 | Food and Chemical Toxicology | 2012 | 8 Pages |
Abstract
⺠Cd is cytotoxic to human mammary cells (MCF10A) decreasing cell viability and proliferation in a dose response manner. ⺠The macrocycle [15]pyN5 presents appropriate chemical and thermodynamic features to be used as a Cd chelator. ⺠[15]pyN5 markedly counteracted the cytotoxic effects induced by Cd.
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![Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of the macrocycle [15]pyN5](/preview/png/5852910.png "First Page Preview: Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of the macrocycle [15]pyN5")
Authors
Sandrina Gonçalves, Ana Sofia Fernandes, Nuno G. Oliveira, Joana Marques, Judite Costa, M. Fátima Cabral, Joana Miranda, Madalena Cipriano, PatrÃcia S. Guerreiro, Matilde Castro,