Assessment of the mutagenic, recombinagenic and carcinogenic potential of orlistat in somatic cells of Drosophila melanogaster

Article ID	Journal	Published Year	Pages	File Type
5852944	Food and Chemical Toxicology	2012	7 Pages	PDF

Abstract

âº The experiments were conducted on Drosophila melanogaster. âº The mutant clones, induced by orlistat, were related to its mitotic recombination. âº The tumor frequencies suggested an absence of carcinogenic potential of orlistat.

Keywords

FAS GSH DXR CYP3A4 Wts FDA standard cross Orlistat Somatic Mutation and Recombination Test Doxorubicin Food and Drug Administration cytochrome P450 3A4 Drosophila melanogaster SMART Stubble Glutathione