| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853064 | Food and Chemical Toxicology | 2011 | 6 Pages |
Abstract
⺠Fucoidan protects myocardial function from rats I/R injury. ⺠The cardioprotection of fucoidan might be due to the regulation of the inflammation mediators. ⺠Fucoidan regulate the inflammation response via HMGB1 and NF-κB inactivation.
Keywords
NF-κBLVSPLVEDPPMNsHMGB1BCATTCIL-6MPOH&EROSInfarct sizeischemia–reperfusioninterleukin 6bicinchoninic acidTriphenyltetrazolium chloridetumor necrosis factor-αhigh-mobility group box 1Heart rateTNF-αnuclear factor kappa Bleft ventricular systolic pressureleft ventricular end-diastolic pressureFucoidanLADmyeloperoxidasemaphematoxylin–eosinInflammation responseHigh mobility group box 1 proteinleft anterior descendingReactive oxygen species
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Authors
Chunmei Li, Yonglin Gao, Yanli Xing, Haibo Zhu, Jingyu Shen, Jingwei Tian,