Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5853078 | Food and Chemical Toxicology | 2011 | 13 Pages |
Abstract
⺠EAGK and 3,5-DCQA attenuated RGC-5 cells death caused by hydrogen peroxide. ⺠EAGK and 3,5-DCQA reduced ROS production, and replenished the reduced glutathione levels. ⺠EAGK and 3,5-DCQA inhibited lipid peroxidation. ⺠EAGK and 3,5-DCQA protected the retina caused by NMDA in vivo.
Keywords
GSHNMDAGCLIPLDCFH-DARP-HPLCN-methyl-d-aspartateRGCsNADPHiOpRGC-5MDA2′,7′-dichlorodihydrofluorescein diacetate3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMTTROSHydrogen peroxideTUNELRetinal ganglion cellsIntraocular pressureinner plexiform layerganglion cell layermalonedialdehydeNeuroprotectionsodium nitroprussidenicotinamide adenine dinucleotide phosphateH2O2Propidium iodideSNPreverse phase-high performance liquid chromatographyGlutathioneGlaucomaReactive oxygen species
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Authors
Kyung-A Kim, Kui Dong Kang, Eun Ha Lee, Chu Won Nho, Sang Hoon Jung,