Article ID Journal Published Year Pages File Type
5853141 Food and Chemical Toxicology 2011 7 Pages PDF
Abstract
► Integerrimine N-oxide (INO) is a pyrrolizidinic alkaloid found in Senecio spp. ► This study showed that INO induces immune and haematological changes in rats. ► Blood cell counts of rats treated with INO were altered. ► INO induces G1 cell cycle arrest with reduction of cells in the S phase. ► INO produces a reducing T cell proliferative activity.
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Life Sciences Agricultural and Biological Sciences Food Science
Preview
Haematological and immunological effects of repeated dose exposure of rats to integerrimine N-oxide from Senecio brasiliensis
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