| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853146 | Food and Chemical Toxicology | 2011 | 8 Pages |
Abstract
⺠Mixtures of POPs from crude and pharmaceutical cod liver oil and its industrial residue affected steroidogenesis in H295R cells. ⺠POP mixtures increased production of progesterone, estradiol and cortisol. ⺠Mixtures increased MC2R, HSD3B2, CYP11B2, CYP11B1, CYP19A1 mRNA levels. ⺠Effect seemed to be elicited by the mayor mixture components, the PCBs.
Keywords
PCBHCHHCBTCDDHBCDRT-PCRDEPCPBDETEQRIAmRNA1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethaneTCDD equivalentsACTHHEPESrelative expression software toolITSDMEMAHR(4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid)2,3,7,8-tetrachlorodibenzodioxincAMPDMSODNAGC–ECDGC–MSDulbecco’s modified Eagle mediumCyclic adenosine monophosphateContaminantsPersistent organic pollutantEstradioldeoxyribonucleic acidribonucleic acidRNAReSTHexachlorobenzenePolychlorinated biphenyltestosteronediethyl-pyrocarbonatePolybrominated diphenyl etherDDTDimethylsulfoxideRadio-immunoassaymessenger ribonucleic acidCod liver oilIndustrial wastegas chromatography–mass spectrometrymixtureadrenocorticotropic hormoneSteroid hormonesHexachlorocyclohexaneHexabromocyclododecanereverse transcription-polymerase chain reactionpopProgesteroneCORTcortisolaryl hydrocarbon receptor
Related Topics
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Food Science
Authors
M. Montaño, K.E. Zimmer, E. Dahl, V. Berg, I. Olsaker, J.U. Skaare, A.J. Murk, E. Ropstad, S. Verhaegen,