| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853167 | Food and Chemical Toxicology | 2011 | 6 Pages |
Abstract
⺠We investigated the effects of cadmium on osteoclast precursor differentiation. ⺠Cadmium could increase tartrate-resistant acid phosphatase activity. ⺠Cadmium could induce osteoclast precursor differentiation to osteoclast. ⺠RANK, TRAF6, Fra1, s-crc, c-fos involves in osteoclast differentiation induced by cadmium.
Keywords
TRAPfos-related antigen 1TRACP 5bFRA1RAW264.7 cellTRAF6RT-PCRRANKLGAPDHFBSDMEMDulbecco’s modified Eagle mediumMTTOsteoclastsTartrate-resistant acid phosphatase 5btartrate-resistant acid phosphataseRankfetal bovine serumtumor necrosis factor receptor associated factor 6methyl thiazolyl tetrazoliumreverse transcription polymerase chain reactionCadmiumglyceraldehyde-3-phosphate dehydrogenase
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Authors
Xiao Chen, Guoying Zhu, Taiyi Jin, Shuzhu Gu, Hanfang Xiao, Jing Qiu,