| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5853330 | Food and Chemical Toxicology | 2012 | 9 Pages |
Abstract
⺠Caffeic acid is one of the most abundant phenolic acid content of most fruit. ⺠Caffeic acid inhibits TPA induced oxidative stress, inflammatory responses, TNF-α release in mouse skin. ⺠Caffeic acid reverses cutaneous histopathological changes. ⺠Caffeic acid attenuates TPA induced expression of NF-κB and COX-2 expression. ⺠Use of caffeic acid may be one of the important therapeutic approaches for cancer prevention.
Keywords
1-chloro 2,4-dinitrobenzeneNF-κBPMNCDNBDTNBGSSGGSTGSHtPANADPHROSEDTAethylenediamine tetra acetic acidinflammationOxidative stresstumor necrosis factor alphaSkin cancerTNF-αpolymorphonuclear leukocyteCaffeic acidreduced nicotinamide adenine dinucleotide phosphatereduced glutathioneglutathione-S-transferaseoxidized glutathioneglutathione reductaseReactive oxygen species
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Authors
Abdul Quaiyoom Khan, Rehan Khan, Wajhul Qamar, Abdul Lateef, Farrah Ali, Mir Tahir, Muneeb-U-Rehman Muneeb-U-Rehman, Sarwat Sultana,