l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes

Article ID	Journal	Published Year	Pages	File Type
5853383	Food and Chemical Toxicology	2012	10 Pages	PDF

Abstract

âº l-Theanine inhibited ethanol-induced liver injury in mice and L02 cells. âº l-Theanine prevents ethanol-induced apoptosis via mitochondrial pathways. âº l-Theanine restored the antioxidant abilities in vitro and in vivo.

Keywords

MMP PBS MDA L02 cells Ethanol-induced liver injury l-theanine PARP PVDF DAPI DCFH-DA ALT CAT GAPDH GSH 2′,7′-dichlorofluorescein diacetate 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide 4′,6′-diamidino-2-phenylindole GSH-Px MTT ROS ALD AST Alanine aminotransferase alcoholic liver disease aspartate transaminase triglyceride Oxidative stress SOD Superoxide dismutase lactate dehydrogenase LDH malondialdehyde Phosphate-buffered saline Mitochondrial membrane potential poly ADP ribose polymerase Polyvinylidene fluoride Catalase Glutathione glutathione reductase glutathione peroxidase Glyceraldehyde phosphate dehydrogenase Reactive oxygen species

Related Topics

Life Sciences Agricultural and Biological Sciences Food Science

l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes

Authors

Guilan Li, Yin Ye, Jingjing Kang, Xiangyang Yao, Yizhou Zhang, Wei Jiang, Min Gao, Yudong Dai, Yinqiang Xin, Qi Wang, Zhimin Yin, Lan Luo,