Article ID Journal Published Year Pages File Type
5853406 Food and Chemical Toxicology 2012 14 Pages PDF
Abstract
► 14-Deoxy-11,12-didehydroandrographolide is cytotoxic against T-47D cells. ► It regulates genes that inhibit the cell cycle or promote cell cycle arrest. ► It regulates genes that reduce or inhibit cell proliferation and induce growth arrest. ► Microscopic analysis reveals highly vacuolated cells and structures similar to apoptotic bodies.
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Life Sciences Agricultural and Biological Sciences Food Science
Preview
Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells
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